Evidence map›Paper›PMID 35733632›Full record

ArticleJournal of neurosurgery. Case lessons2022

Hypertrophic olivary degeneration and palatal myoclonus from a

Annie Tonnu, Rachel Hunt, Thomas Zervos, Travis Hamilton, Christina Tyrrell, Adam M Robin

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of neurosurgery. Case lessons, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Annie TonnuWayne State University School of Medicine, Detroit, Michigan.
Rachel HuntDepartment of Neurological Surgery, Henry Ford Health System, Detroit, Michigan; and.
Thomas ZervosDepartment of Neurological Surgery, Henry Ford Health System, Detroit, Michigan; and.
Travis HamiltonDepartment of Neurological Surgery, Henry Ford Health System, Detroit, Michigan; and.
Christina TyrrellBrainlab, Inc., Westchester, Illinois.
Adam M RobinDepartment of Neurological Surgery, Henry Ford Health System, Detroit, Michigan; and.
Henry Ford Health System · USNeurological Surgery · USWayne State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHypertrophic olivary degeneration (HOD) is a rare condition that can occur after disruption of the Guillain-Mollaret triangle. Clinically, HOD can present with palatal myoclonus with or without oculopalatal tremor, which sometimes results in symptomatic dysphagia and/or speech abnormalities. This condition is commonly associated with vascular lesions, with only three prior reported cases of HOD resulting from intracranial abscess. OBSERVATIONS: An otherwise healthy patient developed multiple intracranial abscesses. Biopsy showed gram-positive cocci; however, culture findings were negative. Polymerase chain reaction (PCR) identified LESSONS: Although HOD classically occurs after vascular insult, it can also be seen as a postinfectious sequela. Despite eradication of the infection, palatal myoclonus and oculopalatal tremor may have a persistent impact on quality of life due to impaired speech and swallowing. This case emphasizes the utility of universal PCR in detecting fastidious organisms as well as diffusion tensor imaging for characterization of disrupted fiber pathways.

Indexed as

brainstemCTT = central tegmental tractdiffusion tensor imagingGMT = Guillain-Mollaret triangleGuillain-Mollaret triangleHOD = hypertrophic olivary degenerationhypertrophic olivary degenerationMRI = magnetic resonance imagingOPT = oculopalatal tremorpalatal myoclonusPCR = polymerase chain reactionPT = palatal tremorSCP = superior cerebellar peduncleStreptococcus intermedius

Identifiers

PMID35733632
PMCPMC9204915
OpenAlexW4283167491

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.