ReviewSocial cognitive and affective neuroscience2022
A missing link in affect regulation: the cerebellum.
Review in Social cognitive and affective neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
23 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The role of the cerebellum in internet gaming disorder-A systematic review.Addiction biology · 2023Pooled it
- Cerebellar Electrical Activity as a Marker for Predicting Brain Health and Disease: A Review.Brain sciences · 2026Review
- Psychosocial Health Following Non-Invasive Brain Stimulation of Oculomotor Regions.Behavioral sciences (Basel, Switzerland) · 2026Article
- Associations between cerebellum and major psychiatric disorders: a bidirectional Mendelian randomization study.European archives of psychiatry and clinical neuroscience · 2026Article
- Predicting entrepreneurship from brain structure and neural responses to risk and ambiguity.Scientific reports · 2025Article
- Longitudinal description of health-related quality of life and depressive symptoms in polyQ spinocerebellar ataxia patients.Journal of neurology · 2025Article
- Individualized cerebellar damage predicts the presence of behavioral disorders in children with brainstem tumors.Communications medicine · 2025Article
- Stress and telomere length in leukocytes: Investigating the role of GABRA6 gene polymorphism and cortisol.Psychoneuroendocrinology · 2025Article
- Cerebellar contribution to emotion regulation and its association with medial frontal GABA level.Social cognitive and affective neuroscience · 2025Article
- Brain metabolic changes associated with post-stroke pathological laughing and crying: anFrontiers in neurology · 2025Article
- Article
- Consensus Paper: Cerebellum and Reward.Cerebellum (London, England) · 2024Review
- Affective Instability: Impact of Fluctuating Emotions on Regulation and Psychological Well-Being.Behavioral sciences (Basel, Switzerland) · 2024Article
- Regional brain activity and connectivity associated with childhood trauma in drug-naive patients with obsessive-compulsive disorder.Scientific reports · 2024Article
- A Novel Unsupervised Machine Learning Approach to Assess Postural Dynamics in Euthymic Bipolar Disorder.IEEE journal of biomedical and health informatics · 2024Article
- AnbioRxiv : the preprint server for biology · 2024Article
- The Cerebellar Response to Visual Portion Size Cues Is Associated with the Portion Size Effect in Children.Nutrients · 2024Article
- Review
- Emotional dysmetria after cerebellar-pontine stroke: a case report.Journal of medical case reports · 2023Article
- Differential engagement of the posterior cingulate cortex during cognitive restructuring of negative self- and social beliefs.Social cognitive and affective neuroscience · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The cerebellum is one-third the size of the cerebrum yet holds twice the number of neurons. Historically, its sole function was thought to be in the calibration of smooth movements through the creation and ongoing modification of motor programs. This traditional viewpoint has been challenged by findings showing that cerebellar damage can lead to striking changes in non-motor behavior, including emotional changes. In this manuscript, we review the literature on clinical and subclinical affective disturbances observed in individuals with lesions to the cerebellum. Disorders include pathological laughing and crying, bipolar disorder, depression and mixed mood changes. We propose a theoretical model based on cerebellar connectivity to explain how the cerebellum calibrates affect. We conclude with actionable steps for future researchers to test this model and improve upon the limitations of past literature.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.