Evidence map›Paper›PMID 35733268›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

Phylogenomic and functional characterization of an evolutionary conserved cytochrome P450-based insecticide detoxification mechanism in bees.

Julian Haas, Angela Hayward, Benjamin Buer, Frank Maiwald, Birgit Nebelsiek, Johannes Glaubitz, Chris Bass, Ralf Nauen

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 81 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Sublethal Concentration of Chloramphenicol Threatens the Health ofInternational journal of molecular sciences · 2026
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Molecular Impact of Sublethal Spinetoram Exposure on Honeybee (International journal of molecular sciences · 2024
    Article
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  14. Article
  15. Review
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Julian HaasInstitute of Crop Science and Resource Conservation, Department of Molecular Phytomedicine, University of Bonn, D-53115 Bonn, Germany.ORCID 0000-0002-8708-3181
Angela HaywardCollege of Life and Environmental Sciences, Biosciences, University of Exeter, Penryn, TR10 9FE, United Kingdom.ORCID 0000-0001-6138-6187
Benjamin BuerCrop Science Division, Research and Development, Bayer AG, D-40789 Monheim, Germany.
Frank MaiwaldCrop Science Division, Research and Development, Bayer AG, D-40789 Monheim, Germany.ORCID 0000-0001-6413-5818
Birgit NebelsiekCrop Science Division, Research and Development, Bayer AG, D-40789 Monheim, Germany.
Johannes GlaubitzCrop Science Division, Research and Development, Bayer AG, D-40789 Monheim, Germany.
Chris BassCollege of Life and Environmental Sciences, Biosciences, University of Exeter, Penryn, TR10 9FE, United Kingdom.
Ralf NauenCrop Science Division, Research and Development, Bayer AG, D-40789 Monheim, Germany.ORCID 0000-0002-7525-8589
North Carolina State University · USUniversity of Exeter · GBUniversity of Bonn · DE

Funding

UKRI | Biotechnology and Biological Sciences Research Council (BBSRC) BB/V004093/1
6 · The paper itself

Abstract

The regulatory process for assessing the risks of pesticides to bees relies heavily on the use of the honeybee,

Indexed as

BeesCytochrome P-450 Enzyme SystemEvolution, MolecularGenes, InsectInactivation, MetabolicInsecticidesInsect ProteinsAnimalsConserved SequenceNeonicotinoidsPhylogenyCytochrome P-450 Enzyme SystemInsecticidesInsect ProteinsNeonicotinoidsbeeneonicotinoidP450

Identifiers

PMID35733268
PMCPMC9245717
OpenAlexW4283325295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.