Evidence map›Paper›PMID 35733209›Full record

Observational studyBMC public health2022

Willingness to accept COVID-19 vaccination among people living with HIV in a high HIV prevalence community.

Sabina Govere-Hwenje, Jana Jarolimova, Joyce Yan, Anele Khumalo, Gugulami Zondi, Marcia Ngcobo, Nafisa J Wara, Dani Zionts, Laura M Bogart, Robert A Parker and 1 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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  20. Determinants of COVID-19 Vaccine Uptake Among People Living with Human Immunodeficiency Virus.Journal of the International Association of Providers of AIDS Care
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Sabina Govere-Hwenje *AIDS Healthcare Foundation, Durban, South Africa. Sabina.Govere@ahf.org.
Jana Jarolimova *Massachusetts General Hospital, Division of Infectious Diseases, Boston, USA.
Joyce YanMassachusetts General Hospital, Biostatistics Center, Boston, USA.
Anele KhumaloAIDS Healthcare Foundation, Durban, South Africa.
Gugulami ZondiAIDS Healthcare Foundation, Durban, South Africa.
Marcia NgcoboAIDS Healthcare Foundation, Durban, South Africa.
Nafisa J WaraMassachusetts General Hospital, Medical Practice Evaluation Center, Boston, USA.
Dani ZiontsMassachusetts General Hospital, Medical Practice Evaluation Center, Boston, USA.
Laura M BogartRAND Corporation, Santa Monica, USA.
Robert A ParkerMassachusetts General Hospital, Biostatistics Center, Boston, USA.
Ingrid V BassettMassachusetts General Hospital, Division of Infectious Diseases, Boston, USA.
Massachusetts General Hospital · USAIDS Healthcare Foundation · ZABoston University · USRAND Corporation · US

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Sung-Jae Lee · 1997 to 2026
$53.5M
PROGRAM FOR AIDS CLINICAL RESEARCH TRAINING (PACRT)T32AI007433 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI MARK J SIEDNER · 1992 to 2026
$11.4M
South Africa's new Central Chronic Medicine Dispensing and Distribution program: assessing the clinic, patient, and community impactR01MH114997 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BASSETT, INGRID VALERIE · 2018 to 2022
$3.4M
Mentoring in patient-oriented research on HIV prevention in the US and South AfricaK24AI141036 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI Ingrid Valerie Bassett · 2019 to 2026
$1.1M
NIAID NIH HHS K24 AI141036NIAID NIH HHS T32 AI007433NIMH NIH HHS P30 MH058107NIMH NIH HHS R01 MH114997
6 · The paper itself

Abstract

backgroundPeople living with HIV (PLWH) may have a poorer prognosis with COVID-19 infection and are an important population for COVID-19 vaccination. We assessed the willingness and reasons for COVID-19 vaccine acceptance or hesitancy among PLWH in South Africa.

methodsWe conducted a cross-sectional study consisting of telephone interviews with a randomly selected subset of participants enrolled in a prospective observational cohort study evaluating a decentralized antiretroviral therapy (ART) delivery program in South Africa. Questions assessed willingness to accept a future COVID-19 vaccine, concerns regarding COVID-19 vaccination, and overall vaccine confidence. Interviews were conducted between September 2020 and January 2021. We evaluated participant demographics, sources of COVID-19 information, stigma and medical mistrust, uptake of non-pharmaceutical interventions, and socioeconomic impacts of the COVID-19 pandemic as potential covariates of willingness to accept vaccination.

resultsWe completed interviews with 213 participants; 153 (72%) were female, median age 35y, and 100 (47%) had completed secondary school. Among the participants, 121 (57%) were willing to accept future vaccination, 46 (22%) were unsure, and 45 (21%) stated they did not intend to be vaccinated. Fear of side effects, reported by 42 (20%), was the most common concern about COVID-19 vaccination. Older age was associated with willingness to accept vaccination (aOR 1.75 for every 10-year increase in age, 95% CI 1.10-2.78, p = 0.02), while higher medical mistrust related to COVID-19 (aOR 0.21, 95% CI 0.093-0.45, p < 0.001) and use of social media for COVID-19 information (aOR 0.30, 95% CI 0.11-0.84, p = 0.02) were associated with lower willingness to accept vaccination.

conclusionsIn this cohort of PLWH in South Africa, over half were willing to accept COVID-19 vaccination, although a substantial proportion remained unsure or were not willing to be vaccinated. Public health messaging should emphasize the safety and efficacy of COVID-19 vaccination and address misinformation and medical mistrust among PLWH. Ongoing efforts to ensure access to COVID-19 vaccines for vulnerable populations are crucial.

Indexed as

COVID-19Influenza, HumanInfluenza VaccinesAdultCOVID-19 VaccinesCross-Sectional StudiesFemaleHealth Knowledge, Attitudes, PracticeHumansMalePandemicsPatient Acceptance of Health CarePrevalenceProspective StudiesTrustVaccinationCOVID-19 VaccinesInfluenza VaccinesCOVID-19HIVSouth AfricaVaccinationvaccine hesitancy

Identifiers

PMID35733209
PMCPMC9214683
OpenAlexW4283361538

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.