Evidence map›Paper›PMID 35733198›Full record

ArticleTrials2022

Tailoring limb length based on total small bowel length in one anastomosis gastric bypass surgery (TAILOR study): study protocol for a randomized controlled trial.

Nienke Slagter, Loek J M de Heide, Ewoud H Jutte, Mirjam A Kaijser, Stefan L Damen, André P van Beek, Marloes Emous

Registry-linked trialOpen access · goldAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06829381 (Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06829381 narecruitingnot on this mapstarted 2025, after this paper: background citation

Tailoring One-Anastomosis Gastric Bypass Based on Total Small Bowel Length - A Randomized Controlled Trial

TypeinterventionalSponsorTel-Aviv Sourasky Medical CenterRan2025 to 2029Enrolled500ConditionsMetabolic and Bariatric SurgeryArmsTailored BPL length, Control - BPL 180 cm
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Trial
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Nienke SlagterCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands. nienke.slagter@mcl.nl.ORCID http://orcid.org/0000-0001-6729-7791
Loek J M de HeideCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.
Ewoud H JutteCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.
Mirjam A KaijserCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.
Stefan L DamenCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.
André P van BeekDepartment of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Marloes EmousCenter for Obesity Northern Netherlands (CON), Medical Center Leeuwarden, Henri Dunantweg 2, 8934, AD, Leeuwarden, The Netherlands.
Medisch Centrum Leeuwarden · NLUniversity Medical Center Groningen · NL

Funding

Research Fund Medical Center Leeuwarden 2020-2
6 · The paper itself

Abstract

backgroundThe one anastomosis gastric bypass (OAGB) is being performed by an increasing number of bariatric centers over the world. However, the optimal length of the biliopancreatic (BP) limb remains a topic of discussion. Retrospective studies suggest the benefit of tailoring BP-limb length; however, randomized trials are lacking. The aim of this study is to investigate whether tailoring the length of the BP-limb based on total small bowel length (TSBL) leads to better results in terms of weight loss, vitamin deficiencies, and bowel movements compared to a fixed BP-limb length.

methodsThe TAILOR study is a double-blind single-center randomized controlled trial. Patients scheduled for primary OAGB surgery will be randomly allocated either to a standard BP-limb of 150 cm or to a BP-limb length based on their TSBL: TSBL < 500 cm, BP-limb 150 cm; TSBL 500-700 cm, BP-limb 180 cm; TSBL > 700 cm, BP-limb 210 cm. The primary outcome is to compare the percent total weight loss (%TWL) at 5 years between the two groups. Secondary outcomes include nutritional deficiencies, remission of comorbidities, symptoms of dumping, quality of life, and daily bowel movements. The study includes a total of 212 patients and is designed to detect a 5% difference in the primary endpoint. DISCUSSION: The TAILOR study will provide new insights into the effect of different BP-limb lengths and the role of the TSBL in the OAGB. The study is designed to provide guidance for bariatric surgeons to determine the optimal BP-limb length in the OAGB.

trial registrationDutch Trial Register NL7945. Prospectively registered on 08 September 2019. NTR (trialregister.nl ).

Indexed as

Gastric BypassObesity, MorbidHumansQuality of LifeRandomized Controlled Trials as TopicRetrospective StudiesWeight LossBariatric surgeryBiliopancreatic limbOne anastomosis gastric bypassTailoring limb lengthTotal small bowel length

Identifiers

PMID35733198
PMCPMC9214974
OpenAlexW4283368832

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.