Evidence map›Paper›PMID 35733160›Full record

ArticleBMC complementary medicine and therapies2022

Ginsenoside Rg-1 prevents elevated cytosolic Ca

A Young Han, Su Min Ha, You Kyoung Shin, Geun Hee Seol

Open access · goldAbstract read
In one paragraph

Article in BMC complementary medicine and therapies, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Ginsenoside RbPharmaceuticals (Basel, Switzerland) · 2023
    Article
  5. Alterations of the CaFrontiers in physiology · 2023
    Article
  6. Astrocytes Reduce Store-Operated CaPharmaceuticals (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

A Young Han *Department of Basic Nursing Science, College of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Su Min Ha *Department of Basic Nursing Science, College of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
You Kyoung Shin *Department of Basic Nursing Science, College of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea.
Geun Hee SeolDepartment of Basic Nursing Science, College of Nursing, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, 02841, Republic of Korea. ghseol@korea.ac.kr.
Korea University · KR

Funding

National Research Foundation of Korea 2020R1I1A1A0107450513National Research Foundation of Korea NRF-2021R1A2C2004118
6 · The paper itself

Abstract

backgroundGinsenoside Rg-1 (Rg-1), a triterpenoid saponin abundantly present in Panax ginseng, is a type of naturally occurring steroid with known anti-diabetic and anti-inflammatory effects. In this study, we sought to confirm the effects and mechanisms of action of Rg-1 on store-operated Ca

methodsCytosolic Ca

resultsHigh glucose significantly increased Ca

conclusionsThese findings indicate that Rg-1 may protect vascular endothelial and smooth muscle cells from Ca

Indexed as

GinsenosidesAdenosine TriphosphatasesAnimalsCalciumGlucoseHumansMiceMyocytes, Smooth MuscleSodium-Calcium ExchangerAdenosine TriphosphatasesCalciumGinsenosidesGlucoseSodium-Calcium ExchangerGinsenoside Rg-1High glucoseStore-operated Ca2+ entryVascular endothelial cellsVascular smooth muscle cells

Identifiers

PMID35733160
PMCPMC9215051
OpenAlexW4283366558

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.