Evidence map›Paper›PMID 35733109›Full record

ArticleBMC gastroenterology2022

Prediction and management of strangulated bowel obstruction: a multi-dimensional model analysis.

Wei-Xuan Xu, Qi-Hong Zhong, Yong Cai, Can-Hong Zhan, Shuai Chen, Hui Wang, Lin Lin, Ying-Qian Geng, Ping Hou, Xian-Qiang Chen and 1 more

Abstract read
In one paragraph

Article in BMC gastroenterology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. High bilirubin and blood urea nitrogen predict intestinal necrosis in incarcerated groin hernia.Hernia : the journal of hernias and abdominal wall surgery · 2026
    Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. A novel scoring system for better management of small bowel obstruction.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
    Article
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Wei-Xuan Xu *Fujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China.
Qi-Hong Zhong *Fujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China.
Yong Cai *Fujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China.
Can-Hong Zhan *Fujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China.
Shuai ChenDepartment of General Surgery (Emergency Surgery), Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
Hui WangDepartment of General Surgery (Emergency Surgery), Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
Lin LinDepartment of Radiology, Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
Ying-Qian GengDepartment of Radiology, Fujian Medical University Union Hospital, No.29 Xinquan Road, Fuzhou, 350001, Fujian Province, China.
Ping HouFujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China.
Xian-Qiang ChenFujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China. cxq760818@163.com.
Jun-Rong ZhangFujian Medical University, No.1 Xuefu bei Road, Fuzhou, 350122, Fujian Province, China. junrongzhang@fjmu.edu.cn.

Funding

Fujian Provincial Young and Middle-aged Key Talents Training Project 2020GGA034Startup Fund for Scientific Research, Fujian Medical University 2019QH1016the Innovation Training and Entrepreneurship Plan for College Students of Fujian Medical University C21045the Joint Funds for the Innovation of Science and Technology, Fujian province 2018Y9006, 2018Y9054
6 · The paper itself

Abstract

backgroundDistinguishing strangulated bowel obstruction (StBO) from simple bowel obstruction (SiBO) still poses a challenge for emergency surgeons. We aimed to construct a predictive model that could distinctly discriminate StBO from SiBO based on the degree of bowel ischemia.

methodsThe patients diagnosed with intestinal obstruction were enrolled and divided into SiBO group and StBO group. Binary logistic regression was applied to identify independent risk factors, and then predictive models based on radiological and multi-dimensional models were constructed. Receiver operating characteristic (ROC) curves and the area under the curve (AUC) were calculated to assess the accuracy of the predicted models. Via stratification analysis, we validated the multi-dimensional model in the prediction of transmural necrosis both in the training set and validation set.

resultsOf the 281 patients with SBO, 45 (16.0%) were found to have StBO, while 236(84.0%) with SiBO. The AUC of the radiological model was 0.706 (95%CI, 0.617-0.795). In the multivariate analysis, seven risk factors including pain duration ≤ 3 days (OR = 3.775), rebound tenderness (OR = 5.201), low-to-absent bowel sounds (OR = 5.006), low levels of potassium (OR = 3.696) and sodium (OR = 3.753), high levels of BUN (OR = 4.349), high radiological score (OR = 11.264) were identified. The AUC of the multi-dimensional model was 0.857(95%CI, 0.793-0.920). In the stratification analysis, the proportion of patients with transmural necrosis was significantly greater in the high-risk group (24%) than in the medium-risk group (3%). No transmural necrosis was found in the low-risk group. The AUC of the validation set was 0.910 (95%CI, 0.843-0.976). None of patients in the low-risk and medium-risk score group suffered with StBO. However, all patients with bowel ischemia (12%) and necrosis (24%) were resorted into high-risk score group.

conclusionThe novel multi-dimensional model offers a useful tool for predicting StBO. Clinical management could be performed according to the multivariate score.

Indexed as

Intestinal ObstructionMesenteric IschemiaHumansIntestine, SmallIschemiaNecrosisRetrospective StudiesIndicationsMulti-dimensional modelRadiologicalRisk factorsStrangulated bowel obstruction

Identifiers

PMID35733109
PMCPMC9219133

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.