Evidence map›Paper›PMID 35732875›Full record

ArticleScientific reports2022

Retrospective evaluation of early thrombosis in transjugular intrahepatic portosystemic polytetrafluoroethylene-coated shunts under 2-day postinterventional heparinization.

Holger Goessmann, Verna Schuffenhauer, Arne Kandulski, Kilian Weigand, Ernst-Michael Jung, Wibke Uller, Gregor Scharf, Cristian Stroszczynski, Niklas Verloh

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Possibility of modern ultrasound imaging of portal venous system.Clinical hemorheology and microcirculation · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Holger GoessmannDepartment of Diagnostic and Interventional Radiology, University of Leipzig Medical Center, Leipzig, Germany.
Verna SchuffenhauerDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany.
Arne KandulskiDepartment of Internal Medicine I, Gastroenterology, Endocrinology, Rheumatology, and Infectious Diseases, Regensburg University Hospital, Regensburg, Germany.
Kilian WeigandDepartment of Internal Medicine I, Gastroenterology, Endocrinology, Rheumatology, and Infectious Diseases, Regensburg University Hospital, Regensburg, Germany.
Ernst-Michael JungDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany.
Wibke UllerDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany.
Gregor ScharfDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany.
Cristian StroszczynskiDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany.
Niklas VerlohDepartment of Radiology, University Hospital Regensburg, 93042, Regensburg, Germany. niklas.verloh@ukr.de.
University Hospital Regensburg · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of acute thrombosis within the TIPS tract may be prevented by prophylactic anticoagulation; however, there is no evidence of the correct anticoagulation regimen after TIPS placement. The purpose of this single-center retrospective study was to evaluate the short-term occlusion rate of transjugular intrahepatic portosystemic shunts (TIPSs) with polytetrafluorethylene (PTFE)-coated stents under consequent periprocedural full heparinization (target partial thromboplastin time [PTT]: 60-80 s). We analyzed TIPS placements that were followed up over a six-month period by Doppler ultrasound in 94 patients and compared the study group of 54 patients who received intravenous periprocedural full heparinization (target PTT: 60-80 s) without any other anticoagulation to patients with prolonged anticoagulation medication. The primary endpoint was TIPS patency after six months. The primary patency rate was 88.3% overall, and in the study group, 90.7%, with an early thrombosis rate of 3.2% (study group: 1.9%) and a primary assisted patency rate of 95.7% (study group: 96.3%). In the study group, one case of TIPS thrombosis occurred on the 23rd day after TIPS placement. Two patients underwent reintervention because of stenosis or buckling. Moreover, the target PTT was not attained in 8 of the 54 patent TIPSs. Four patients had an increased portosystemic pressure gradient, without stenosis, and the flow rate was corrected by increasing the TIPS diameter by dilation. Two-day heparinization seems sufficient to avoid early TIPS thrombosis over a six-month period.

Indexed as

Hypertension, PortalPortasystemic Shunt, Transjugular IntrahepaticThrombosisAnticoagulantsConstriction, PathologicHumansPolytetrafluoroethyleneRetrospective StudiesStentsTreatment OutcomeAnticoagulantsPolytetrafluoroethylene

Identifiers

PMID35732875
PMCPMC9217914
OpenAlexW4283386149

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.