Evidence map›Paper›PMID 35732795›Full record

ArticleScientific reports2022

Large-scale investigation of deep learning approaches for ventilated lung segmentation using multi-nuclear hyperpolarized gas MRI.

Joshua R Astley, Alberto M Biancardi, Paul J C Hughes, Helen Marshall, Laurie J Smith, Guilhem J Collier, James A Eaden, Nicholas D Weatherley, Matthew Q Hatton, Jim M Wild and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Pulmonary MRI in Newborns and Children.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  7. Magnetic resonance in medicine · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joshua R AstleyDepartment of Oncology and Metabolism, The University of Sheffield, Sheffield, UK.
Alberto M BiancardiPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Paul J C HughesPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Helen MarshallPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Laurie J SmithPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Guilhem J CollierPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
James A EadenPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Nicholas D WeatherleyPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Matthew Q HattonDepartment of Oncology and Metabolism, The University of Sheffield, Sheffield, UK.
Jim M WildPOLARIS, Department of Infection, Immunity and Cardiovascular Disease, The University of Sheffield, Sheffield, UK.
Bilal A TahirDepartment of Oncology and Metabolism, The University of Sheffield, Sheffield, UK. b.tahir@sheffield.ac.uk.

Funding

British Heart Foundation SP/14/6/31350Department of Health NIHR-RP-R3-12-027Medical Research Council MR/M008894/1
6 · The paper itself

Abstract

Respiratory diseases are leading causes of mortality and morbidity worldwide. Pulmonary imaging is an essential component of the diagnosis, treatment planning, monitoring, and treatment assessment of respiratory diseases. Insights into numerous pulmonary pathologies can be gleaned from functional lung MRI techniques. These include hyperpolarized gas ventilation MRI, which enables visualization and quantification of regional lung ventilation with high spatial resolution. Segmentation of the ventilated lung is required to calculate clinically relevant biomarkers. Recent research in deep learning (DL) has shown promising results for numerous segmentation problems. Here, we evaluate several 3D convolutional neural networks to segment ventilated lung regions on hyperpolarized gas MRI scans. The dataset consists of 759 helium-3 (

Indexed as

Deep LearningHumansLungLung Volume MeasurementsMagnetic Resonance ImagingMale

Identifiers

PMID35732795
PMCPMC9217976

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.