Evidence map›Paper›PMID 35732736›Full record

ArticleNature2022

Biosynthetic potential of the global ocean microbiome.

Lucas Paoli, Hans-Joachim Ruscheweyh, Clarissa C Forneris, Florian Hubrich, Satria Kautsar, Agneya Bhushan, Alessandro Lotti, Quentin Clayssen, Guillem Salazar, Alessio Milanese and 23 more

Abstract read
In one paragraph

Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 210 papers.

0numbers the graph read from it
0cells of the map it votes in
210citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

210 citing papers in PubMed.

  1. Article
  2. Biosynthetic origin of anticancer dolastatin 15 reveals a noncanonical NRPS architecture enabling 2-keto acid activation.Proceedings of the National Academy of Sciences of the United States of America · 2026
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150 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

33 authors.

Lucas PaoliDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-0771-8309
Hans-Joachim Ruscheweyh *Department of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-7473-6086
Clarissa C Forneris *Department of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Florian Hubrich *Department of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Satria KautsarBioinformatics Group, Wageningen University, Wageningen, The Netherlands.
Agneya BhushanDepartment of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Alessandro LottiDepartment of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland.
Quentin ClayssenDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.
Guillem SalazarDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-9786-1493
Alessio MilaneseDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-7050-2239
Charlotte I CarlströmDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.
Chrysa PapadopoulouDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-3909-7378
Daniel GehrigDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.
Mikhail KarasikovDepartment of Computer Science, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-6200-5972
Harun MustafaDepartment of Computer Science, ETH Zurich, Zurich, Switzerland.
Martin LarraldeStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-3947-4444
Laura M CarrollStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.
Pablo SánchezDepartment of Marine Biology and Oceanography, Institute of Marine Sciences ICM-CSIC, Barcelona, Spain.ORCID http://orcid.org/0000-0003-2787-822X
Ahmed A ZayedCenter of Microbiome Science, EMERGE Biology Integration Institute, Department of Microbiology, The Ohio State University, Columbus, OH, USA.ORCID http://orcid.org/0000-0003-2793-2679
Dylan R CroninCenter of Microbiome Science, EMERGE Biology Integration Institute, Department of Microbiology, The Ohio State University, Columbus, OH, USA.
Silvia G AcinasDepartment of Marine Biology and Oceanography, Institute of Marine Sciences ICM-CSIC, Barcelona, Spain.ORCID http://orcid.org/0000-0002-3439-0428
Peer BorkStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0002-2627-833X
Chris BowlerInstitut de Biologie de l'ENS (IBENS), Département de biologie, École normale supérieure, CNRS, INSERM, Université PSL, Paris, France.ORCID http://orcid.org/0000-0003-3835-6187
Tom O DelmontResearch Federation for the Study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, Paris, France.ORCID http://orcid.org/0000-0001-7053-7848
Josep M GasolDepartment of Marine Biology and Oceanography, Institute of Marine Sciences ICM-CSIC, Barcelona, Spain.ORCID http://orcid.org/0000-0001-5238-2387
Alvar D GossertDepartment of Biology, Biomolecular NMR Spectroscopy Platform, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-7732-495X
André KahlesDepartment of Computer Science, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-3411-0692
Matthew B SullivanDepartment of Marine Biology and Oceanography, Institute of Marine Sciences ICM-CSIC, Barcelona, Spain.ORCID http://orcid.org/0000-0001-8398-8234
Patrick WinckerResearch Federation for the Study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, Paris, France.
Georg ZellerStructural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany.ORCID http://orcid.org/0000-0003-1429-7485
Serina L RobinsonDepartment of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland. Serina.Robinson@eawag.ch.ORCID http://orcid.org/0000-0001-6947-7913
Jörn PielDepartment of Biology, Institute of Microbiology, ETH Zurich, Zurich, Switzerland. jpiel@ethz.ch.ORCID http://orcid.org/0000-0002-2282-8154
Shinichi SunagawaDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland. ssunagawa@ethz.ch.ORCID http://orcid.org/0000-0003-3065-0314

Funding

European Research Council 835067
6 · The paper itself

Abstract

Natural microbial communities are phylogenetically and metabolically diverse. In addition to underexplored organismal groups

Indexed as

Biosynthetic PathwaysMicrobiotaOceans and SeasBacteriaGenomicsMultigene FamilyPhylogeny

Identifiers

PMID35732736
PMCPMC9259500

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.