ArticleNature2022
cBAF complex components and MYC cooperate early in CD8
Erratum issuedOpen access · greenAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 119 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
0cells of the map it votes in
119citing papers in PubMed, 1 pooled it
15.1field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
119 citing papers in PubMed, 1 synthesis or guideline pooled it, 154 citations in OpenAlex.
- Strategies and mechanisms for the enhancement of chimeric antigen receptor T-cell functions.Science China. Life sciences · 2026Pooled it
- Article
- High-Content CRISPR Screening: Methods and Applications.MedComm · 2026Review
- Fate induction through asymmetric T cell division is modulated by chimeric antigen receptor costimulatory domains.Nature immunology · 2026Article
- Granzyme A-expressing Terminal Effector T Cells Dedifferentiate into Long-lived Memory T Cells.Research square · 2026Article
- Single-cell gain-of-function mapping reveals latent regulatory programs governing CD8Research square · 2026Article
- CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- Mitochondrial ATP production promotes T cell differentiation and function by regulating chromatin accessibility.bioRxiv : the preprint server for biology · 2026Article
- Canonical BAF chromatin remodeling complex specifies stem cell fate via cell-type-specific co-factor recruitment.Nature communications · 2026Article
- Single-Cell Multiomics Decoding of TCIRG1-Mediated Cuproptosis Circuitry Rewiring Immune-Metabolic Landscape in Ischemic Stroke.Translational stroke research · 2026Article
- Stepwise differentiation from precursor intermediates and distinct Th1 checkpoints promote CD4 Th1 cell differentiation during chronic viral infection.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Regulators of CD8Nature reviews. Immunology · 2026Review
- Latent Regulatory Programs Generate Synthetic T Cell States with Enhanced Therapeutic Potential.bioRxiv : the preprint server for biology · 2026Article
- Mechanisms of T cell activation: Integrating signaling pathways, experimental models, and therapeutic implications.EXCLI journal · 2026Review
- Tumor-immune metabolic tug-of-war: from immune escape to targeting metabolic rewiring in cancer therapy.Frontiers in cell and developmental biology · 2026Review
- High-throughput screening to engineer optimal T cell therapies: current knowledge and future prospects.Frontiers in oncology · 2026Review
- Next-generation CAR-T engineering for colorectal cancer: integrating targets, tumor microenvironment barriers, and emerging strategies.Frontiers in immunology · 2026Review
- BRD9 at the crossroads of splicing, chromatin remodeling, and hematopoiesis.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2026Review
- Epigenetic regulation of T cell exhaustion in cancer.Nature reviews. Cancer · 2026Review
- Transcriptomics and single-cell RNA sequencing uncover prognostic characteristics and immune regulatory mechanisms of lactylation in cervical cancer.BioImpacts : BI · 2026Article
59 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
22 authors at 2 institutions in 1 country.
Ao Guo *Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-2597-7558
Hongling Huang *Department of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Zhexin ZhuComprehensive Cancer Center and Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.
Mark J ChenDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-1169-563X
Hao ShiDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-2796-629X
Sujing YuanDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Piyush SharmaDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Jon P ConnellyCenter for Advanced Genome Engineering, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-5564-1775
Swantje LiedmannDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Yogesh DhunganaDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Zhenrui LiDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Dalia HaydarDepartment of Bone Marrow Transplantation and Cellular Therapy, St Jude Children's Research Hospital, Memphis, TN, USA.
Mao YangDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Helen BeereDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.
Jason T YusteinBaylor Texas Children's Cancer and Hematology Centers, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Christopher DeRenzoDepartment of Bone Marrow Transplantation and Cellular Therapy, St Jude Children's Research Hospital, Memphis, TN, USA.
Shondra M Pruett-MillerCenter for Advanced Genome Engineering, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0002-3793-585X
Jeremy Chase CrawfordDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4096-6048
Giedre KrenciuteDepartment of Bone Marrow Transplantation and Cellular Therapy, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-4335-0644
Charles W M RobertsComprehensive Cancer Center and Department of Oncology, St Jude Children's Research Hospital, Memphis, TN, USA.ORCID http://orcid.org/0000-0003-1135-1896
Hongbo ChiDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA. hongbo.chi@stjude.org.ORCID http://orcid.org/0000-0002-9997-2496
Douglas R GreenDepartment of Immunology, St Jude Children's Research Hospital, Memphis, TN, USA. douglas.green@stjude.org.ORCID http://orcid.org/0000-0002-7332-1417
St. Jude Children's Research Hospital · USBaylor College of Medicine · US
Funding
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Shondra Michelle Miller · 1985 to 2026
$166.9MMECHANISMS OF REGULATED CELL DEATHR35CA231620 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Douglas R. Green · 2018 to 2026
$9.2MIntegrating systems immunology with immunometabolism and cancer immunityR35CA253188 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Hongbo Chi · 2021 to 2026
$6.0MEstablishment, maintenance, and consequences of asymmetric cell division in T cellsR01AI123322 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI GREEN, DOUGLAS R. · 2017 to 2021
$2.2MImproving CAR T cell therapy for brain tumors using immune competent modelsR00CA256262 · NCI · CHILDREN'S RESEARCH INSTITUTE · PI HAYDAR, DALIA · 2023 to 2025
$713kImproving CAR T cell therapy for brain tumors using immune competent modelsK99CA256262 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI HAYDAR, DALIA · 2021 to 2022
$250kNCI NIH HHS K99 CA256262NCI NIH HHS P30 CA021765NCI NIH HHS R00 CA256262NCI NIH HHS R35 CA231620NCI NIH HHS R35 CA253188NIAID NIH HHS R01 AI123322NIH HHS CA231620NIH HHS CA253188
Abstract
The identification of mechanisms to promote memory T (T
Indexed as
CD8-Positive T-LymphocytesCell DifferentiationDNA HelicasesMultiprotein ComplexesNuclear ProteinsProto-Oncogene Proteins c-mycTranscription FactorsAnimalsDisease Models, AnimalImmunologic MemoryImmunotherapyMemory T CellsMiceNeoplasmsReceptors, Chimeric AntigenDNA HelicasesMultiprotein ComplexesMyc protein, mouseNuclear ProteinsProto-Oncogene Proteins c-mycReceptors, Chimeric AntigenSmarca2 protein, mouseSmarca4 protein, mouseTranscription Factors
Identifiers
What OpenQuestion holds
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Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.