Evidence map›Paper›PMID 35732709›Full record

ArticleScientific reports2022

Protocatechuic acid as a potent anticarcinogenic compound in purple rice bran against diethylnitrosamine-initiated rat hepatocarcinogenesis.

Charatda Punvittayagul, Theerapat Luangsuphabool, Rawiwan Wongpoomchai

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  5. Article
  6. Enhancement Strategy for Protocatechuic Acid Production UsingInternational journal of molecular sciences · 2025
    Article
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  8. Review
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  10. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Charatda PunvittayagulResearch Affairs, Faculty of Veterinary Medicine, Chiang Mai University, Chiang Mai, 50100, Thailand.
Theerapat LuangsuphaboolBiotechnology Research and Development Office, Department of Agriculture, Rangsit, Thanyaburi, Pathum Thani, 12110, Thailand.
Rawiwan WongpoomchaiDepartment of Biochemistry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand. rawiwan.wong@cmu.ac.th.
Chiang Mai University · THEastern Asia University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our previous study demonstrated that purple rice bran extract (PRBE) could inhibit diethylnitrosamine (DEN)-induced hepatocarcinogenesis. Protocatechuic acid (PCA) is the major phenolic acid contained in the PRBE. Therefore, this study aimed to determine whether PCA is an anticarcinogenic compound in purple rice extract. Rats were intraperitoneally injected with DEN to induce glutathione S-transferase placental form (GST-P)-positive foci. Rats were fed with PRBE at 500 mg kg

Indexed as

Anticarcinogenic AgentsLiver Neoplasms, ExperimentalOryzaAnimalsBody WeightCarcinogenesisDiethylnitrosamineFemaleGlutathione TransferaseHydroxybenzoatesLiverPlacentaPlant ExtractsPregnancyRatsAnticarcinogenic AgentsDiethylnitrosamineGlutathione TransferaseHydroxybenzoatesPlant Extractsprotocatechuic acid

Identifiers

PMID35732709
PMCPMC9217852
OpenAlexW4283330805

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.