ArticleNature communications2022
Dissociation between individual differences in self-reported pain intensity and underlying fMRI brain activation.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed.
- Comparison of behavioural, physiological, and self-reported pain responses in Pakistani children with dental pain: a descriptive cross-sectional study.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2025Trial
- Mindfulness Meditation and Placebo Modulate Distinct Multivariate Neural Signatures to Reduce Pain.Biological psychiatry · 2025Trial
- Neural encoding of pain is robust within but unstable between individuals.PLoS biology · 2026Article
- EEG-based clustering shows distinct separation of chronic pain patients before spinal cord stimulation surgery.NeuroImage · 2026Article
- Why pain biomarkers cannot replace the patient experience.Nature neuroscience · 2026Article
- Presurgical immune biomarkers associated with pain intensity and pain interference recovery after total knee arthroplasty: findings from the PRIME-KNEE study.medRxiv : the preprint server for health sciences · 2026Article
- An exploratory study of headache pain intensity using facial expressions and APEX frames.NPJ digital medicine · 2026Article
- Empathy-related individual differences in brain responses to robot and human pain.Frontiers in human neuroscience · 2026Article
- A Replicable and Generalizable Neuroimaging-Based Indicator of Pain Sensitivity Across Individuals.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Neural variability reliably encodes interindividual differences in the perception of pain intensity.PLoS biology · 2025Article
- The brain's action-mode network.Nature reviews. Neuroscience · 2025Review
- Association of Pharmacogenotyping and Patient-Reported Outcomes in Chronic Pain Management.Health services insights · 2025Article
- Proceedings of the 12th annual deep brain stimulation think tank: cutting edge technology meets novel applications.Frontiers in human neuroscience · 2025Article
- Neural basis of intensity-dependent brain activity in response to mechanical stimulation and the level of pain sensitivity.Frontiers in human neuroscience · 2025Article
- Advances and challenges in neuroimaging-based pain biomarkers.Cell reports. Medicine · 2024Review
- Interindividual differences in pain can be explained by fMRI, sociodemographic, and psychological factors.Nature communications · 2024Article
- Radiation of pain: Psychophysical evidence for a population coding mechanism in humans.bioRxiv : the preprint server for biology · 2024Article
- Altitude illnesses.Nature reviews. Disease primers · 2024Review
- Weak Relationships Between Psychological Factors and Experimental Pain Outcomes in Pain-Free Individuals: An Aggregate Analysis of 8 Studies.The journal of pain · 2024Article
- May Spasticity-Related Unpleasant Sensations Interfere with Daily Activities in People with Stroke and Traumatic Brain Injury? Secondary Analysis from the CORTOX Study.Journal of clinical medicine · 2024Article
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Abstract
Pain is an individual experience. Previous studies have highlighted changes in brain activation and morphology associated with within- and interindividual pain perception. In this study we sought to characterize brain mechanisms associated with between-individual differences in pain in a sample of healthy adolescent and adult participants (N = 101). Here we show that pain ratings varied widely across individuals and that individuals reported changes in pain evoked by small differences in stimulus intensity in a manner congruent with their pain sensitivity, further supporting the utility of subjective reporting as a measure of the true individual experience. Furthermore, brain activation related to interindividual differences in pain was not detected, despite clear sensitivity of the Blood Oxygenation Level-Dependent (BOLD) signal to small differences in noxious stimulus intensities within individuals. These findings suggest fMRI may not be a useful objective measure to infer reported pain intensity.
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