Evidence map›Paper›PMID 35732446›Full record

ArticleInternal medicine (Tokyo, Japan)2023

Cardiac Tamponade as a Recurrence of Angioimmunoblastic T-Cell Lymphoma with the Detection of a p.Gly17Val RHOA Mutation in the Pericardial Effusion.

Yuri Tsuboi, Yumoe Iimura, Fumiaki Matsumura, Toru Nanmoku, Sakurako Suma, Ryota Matsuoka, Tomoki Nakagawa, Daishi Nakagawa, Yasuhito Suehara, Keiichiro Hattori and 11 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 2 institutions in 1 country.

Yuri TsuboiDepartment of Hematology, University of Tsukuba Hospital, Japan.
Yumoe IimuraDepartment of Hematology, University of Tsukuba Hospital, Japan.
Fumiaki MatsumuraDepartment of Hematology, University of Tsukuba Hospital, Japan.
Toru NanmokuDepartment of Clinical Laboratory, University of Tsukuba Hospital, Japan.
Sakurako SumaDepartment of Hematology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan.
Ryota MatsuokaDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Japan.
Tomoki NakagawaDepartment of Pathology, Faculty of Medicine, University of Tsukuba, Japan.
Daishi NakagawaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Japan.
Yasuhito SueharaDepartment of Hematology, University of Tsukuba Hospital, Japan.
Keiichiro HattoriDepartment of Hematology, University of Tsukuba Hospital, Japan.
Kimi SatoDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Japan.
Yumiko MaruyamaDepartment of Hematology, University of Tsukuba Hospital, Japan.
Tatsuhiro SakamotoDepartment of Hematology, University of Tsukuba Hospital, Japan.
Yasuhisa YokoyamaDepartment of Hematology, University of Tsukuba Hospital, Japan.
Takayasu KatoDepartment of Hematology, University of Tsukuba Hospital, Japan.
Naoki KuritaDepartment of Hematology, University of Tsukuba Hospital, Japan.
Hidekazu NishikiiDepartment of Hematology, University of Tsukuba Hospital, Japan.
Naoshi ObaraDepartment of Hematology, University of Tsukuba Hospital, Japan.
Masaki IedaDepartment of Cardiology, Faculty of Medicine, University of Tsukuba, Japan.
Shigeru ChibaDepartment of Hematology, University of Tsukuba Hospital, Japan.
Mamiko Sakata-YanagimotoDepartment of Hematology, University of Tsukuba Hospital, Japan.
University of Tsukuba Hospital · JPUniversity of Tsukuba · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is an intractable type of T-cell lymphoma. We and others have identified that the p.Gly17Val RHOA mutation is specifically identified in AITL. We herein report a patient whose condition deteriorated, resulting from massive pericardial effusion one month after undergoing autologous transplantation for AITL. He was diagnosed with cardiac tamponade caused by AITL recurrence in the presence of the p.Gly17Val RHOA mutation as well as T-lineage cells with an aberrant immune-phenotype in the pericardial effusion. This case suggests that a precision medicine approach by detecting the presence of a p.Gly17Val RHOA mutation is useful for the management of AITL.

Indexed as

Cardiac TamponadeImmunoblastic LymphadenopathyLymphoma, T-CellPericardial EffusionHumansMaleMutationrhoA GTP-Binding ProteinrhoA GTP-Binding ProteinRHOA protein, humanAITLlymphomap.Gly17Val RHOA mutationprecision medicine

Identifiers

PMID35732446
PMCPMC10017241
OpenAlexW4283364377

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.