Evidence map›Paper›PMID 35732389›Full record

ArticleBMJ open2022

Psychological interventions for inflammatory bowel disease: a systematic review and component network meta-analysis protocol.

Natalia Tiles-Sar, Johanna Neuser, Dominik de Sordi, Gerta Rücker, Anne Baltes, Jan Preiss, Gabriele Moser, Antje Timmer

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Psychological interventions for treatment of inflammatory bowel disease.The Cochrane database of systematic reviews · 2025
    Pooled it
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 2 countries.

Natalia Tiles-SarDepartment of Epidemiology and Biometry, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany natalia.tiles-sar@uni-oldenburg.de.ORCID 0000-0001-6128-114X
Johanna NeuserDepartment of Epidemiology and Biometry, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany.
Dominik de SordiDepartment of Epidemiology and Biometry, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany.
Gerta RückerInstitute of Medical Biometry and Medical Informatics, Medical Faculty and Medical Center - University of Freiburg, Freiburg, Germany.ORCID 0000-0002-2192-2560
Anne BaltesGerman Association for Crohn's Disease and Ulcerative Colitis (DCCV e.V.), Berlin, Germany.
Jan PreissClinic for Internal Medicine - Gastroenterology, Diabetology and Hepatology, Vivantes Klinikum Neukölln, Berlin, Germany.
Gabriele MoserDepartment of Internal Medicine III, Division of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria.
Antje TimmerDepartment of Epidemiology and Biometry, Carl von Ossietzky University of Oldenburg, Oldenburg, Germany.
Carl von Ossietzky Universität Oldenburg · DEDeutsche Morbus Crohn/Colitis ulcerosa Vereinigung · DEMedical University of Vienna · ATUniversity of Freiburg · DEVivantes Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPatients with inflammatory bowel diseases (IBD) often report psychological problems, unemployment, disability, sick leave and compromised quality of life. The effect of psychological interventions on health-related outcomes in IBD is controversial as previous reviews faced the obstacle of high heterogeneity among provided multimodular interventions. The heterogeneity can be addressed with network meta-analysis (NMA) and (multi)component NMA (CNMA). We aim to investigate whether psychological interventions can improve quality of life, clinical and social outcomes in IBD using NMA and CNMA. This is the study protocol. METHODS AND ANALYSIS: We will consider randomised, quasi-randomised and non-randomised controlled trials, including cluster randomised and cross-over trials with 2 months of minimum follow-up. The conditions to be studied comprise Crohn's disease and ulcerative colitis in children, adolescents and adults. We will include any psychological intervention aiming to change the health status of the study participant.We will search Medline, Embase, Web of Science, CENTRAL, LILACS, Psyndex, PsycINFO, Google Scholar and trial registries from inception (the search will be updated before the review completion). Two authors will independently screen all references based on titles and abstracts. For data extraction, standard forms are developed and tested before extraction. All information will be assessed independently by at least two reviewers, and disagreements solved by consensus discussion or a third rater if necessary.The data synthesis will include a pairwise meta-analysis supported by meta-regression. We will conduct NMA (all treatments will constitute single nodes of the network) and CNMA (we will define all treatments as sums of core components, eg, cognitive +behaviour, or cognitive +behaviour + relaxation, and additionally consider interactions) using the R Package netmeta. ETHICS AND DISSEMINATION: No ethical approval is required. Reports will include the final report to the funder, conference presentation, peer-reviewed publication and a patient report. PROSPERO REGISTRATION NUMBER: CRD42021250446.

Indexed as

Inflammatory Bowel DiseasesPsychosocial InterventionAdolescentAdultChildChronic DiseaseHumansNetwork Meta-Analysis as TopicQuality of LifeSystematic Reviews as Topicanxiety disordersdepression & mood disordersinflammatory bowel diseasemental healthrehabilitation medicine

Identifiers

PMID35732389
PMCPMC9226957
OpenAlexW4283269458

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.