Evidence map›Paper›PMID 35732255›Full record

ArticleAmerican journal of infection control2023

Investigation of a cluster of rapidly growing mycobacteria infections associated with joint replacement surgery in a Kentucky hospital, 2013-2014 with 8-year follow-up.

Matthew R Groenewold, Andrea Flinchum, Aravind Pillai, Stacey Konkle, Heather Moulton-Meissner, Pritish K Tosh, Douglas A Thoroughman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of infection control, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. IJID regions · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Matthew R GroenewoldCareer Epidemiology Field Officer Program, Centers for Disease Control and Prevention, Frankfort, KY, USA; Division of Epidemiology and Health Planning, Kentucky Department for Public Health, Frankfort, KY, USA. Electronic address: gyr5@cdc.gov.
Andrea FlinchumDivision of Epidemiology and Health Planning, Kentucky Department for Public Health, Frankfort, KY, USA.
Aravind PillaiDivision of Epidemiology and Health Planning, Kentucky Department for Public Health, Frankfort, KY, USA.
Stacey KonkleDivision of Epidemiology and Health Planning, Kentucky Department for Public Health, Frankfort, KY, USA.
Heather Moulton-MeissnerDivision of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA, USA.
Pritish K ToshDivision of Infectious Diseases, Mayo Clinic, Rochester, MN, USA.
Douglas A ThoroughmanCareer Epidemiology Field Officer Program, Centers for Disease Control and Prevention, Frankfort, KY, USA; Division of Epidemiology and Health Planning, Kentucky Department for Public Health, Frankfort, KY, USA.
Centers for Disease Control and Prevention · USKentucky Department for Public Health · USMayo Clinic in Florida · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundWe describe the investigation of a nosocomial outbreak of rapidly growing mycobacteria (RGM) infections and the results of mitigation efforts after 8 years.

methodsA cluster of RGM cases in a Kentucky hospital in 2013 prompted an investigation into RGM surgical site infections following joint replacement surgery. A case-control study was conducted to identify risk factors.

resultsEight cases were identified, 5 caused by M. wolinskyi and 3 by M. goodii. The case-control study showed the presence of a particular nurse in the operating room was significantly associated with infection. Environmental sampling at the nurse's home identified an outdoor hot tub as the likely source of M. wolinskyi, confirmed by pulsed-field gel electrophoresis and whole genome sequencing. The hot tub reservoir was eliminated, and hospital policies were revised to correct infection control lapses. No new cases of RGM infections have been identified as of 2021. DISCUSSION: Breaches in infection control practices at multiple levels may have led to a chain of infection from a nurse's hot tub to surgical sites via indirect person-to-person transmission from a colonized health care worker (HCW).

conclusionsThe multifactorial nature of the outbreak's cause highlights the importance of overlapping or redundant layers of protection preventing patient harm. Future investigations of RGM outbreaks should consider the potential role of colonized HCWs as a transmission vector.

Indexed as

Arthroplasty, ReplacementMycobacterium Infections, NontuberculousCase-Control StudiesDisease OutbreaksFollow-Up StudiesHospitalsHumansKentuckyNontuberculous MycobacteriaHealthcare-associated infectionsM. wolinskyiNon-tuberculosis mycobacteriaOutbreak investigationSurgical site infection

Identifiers

PMID35732255
PMCPMC9896514
OpenAlexW4283123818

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.