Evidence map›Paper›PMID 35732133›Full record

ArticleCell reports2022

Quantitative relationship between cerebrovascular network and neuronal cell types in mice.

Yuan-Ting Wu, Hannah C Bennett, Uree Chon, Daniel J Vanselow, Qingguang Zhang, Rodrigo Muñoz-Castañeda, Keith C Cheng, Pavel Osten, Patrick J Drew, Yongsoo Kim

Abstract read
In one paragraph

Article in Cell reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

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  12. Type-I nNOS neurons orchestrate cortical neural activity and vasomotion.bioRxiv : the preprint server for biology · 2025
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  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yuan-Ting WuDepartment of Neural and Behavioral Sciences, The Pennsylvania State University, Hershey, PA 17033, USA.
Hannah C BennettDepartment of Neural and Behavioral Sciences, The Pennsylvania State University, Hershey, PA 17033, USA.
Uree ChonDepartment of Neural and Behavioral Sciences, The Pennsylvania State University, Hershey, PA 17033, USA.
Daniel J VanselowDepartment of Pathology, The Pennsylvania State University, Hershey, PA 17033, USA.
Qingguang ZhangCenter for Neural Engineering, Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA.
Rodrigo Muñoz-CastañedaCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Keith C ChengDepartment of Pathology, The Pennsylvania State University, Hershey, PA 17033, USA.
Pavel OstenCold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724, USA.
Patrick J DrewCenter for Neural Engineering, Department of Engineering Science and Mechanics, The Pennsylvania State University, University Park, PA 16802, USA; Department of Biomedical Engineering, The Pennsylvania State University, University Park, PA 16802, USA; Department of Neurosurgery, The Pennsylvania State University, University Park, PA 16802, USA.
Yongsoo KimDepartment of Neural and Behavioral Sciences, The Pennsylvania State University, Hershey, PA 17033, USA. Electronic address: yuk17@psu.edu.

Funding

Collaboratory for atlasing cell type anatomy in the female and male mouse brainU01MH114824 · NIMH · COLD SPRING HARBOR LABORATORY · PI MITRA, PARTHA PRATIM · 2017 to 2021
$11.7M
Establishing Common Coordinate Framework for Quantitative Cell Census in Developing Mouse BrainsRF1MH124605 · NIMH · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI GEE, JAMES C, KIM, YONGSOO · 2020 to 2020
$3.8M
Imaging neurovascular coupling and functional connectivity in the behaving mouseR01NS078168 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI DREW, PATRICK JAMES · 2013 to 2023
$3.3M
Understanding cellular architecture of the neurovascular unit and its function in the whole mouse brainR01NS108407 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI KIM, YONGSOO · 2018 to 2022
$3.1M
A multimodal approach to understanding the development of neurovascular couplingR01NS101353 · NINDS · PENNSYLVANIA STATE UNIVERSITY, THE · PI DREW, PATRICK JAMES, ZHANG, NANYIN · 2017 to 2021
$2.2M
NIMH NIH HHS RF1 MH124605NIMH NIH HHS U01 MH114824NINDS NIH HHS R01 NS078168NINDS NIH HHS R01 NS101353NINDS NIH HHS R01 NS108407
6 · The paper itself

Abstract

The cerebrovasculature and its mural cells must meet brain regional energy demands, but how their spatial relationship with different neuronal cell types varies across the brain remains largely unknown. Here we apply brain-wide mapping methods to comprehensively define the quantitative relationships between the cerebrovasculature, capillary pericytes, and glutamatergic and GABAergic neurons, including neuronal nitric oxide synthase-positive (nNOS

Indexed as

GABAergic NeuronsParvalbuminsAnimalsBrainCerebral CortexMicePericytesParvalbuminsbrain mappingcell typescerebral vasculatureCP: Neuroscienceflow simulationmicrovesselnNOSparvalbuminpericyteserial two-photon tomography

Identifiers

PMID35732133
PMCPMC9271215

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.