Evidence map›Paper›PMID 35731809›Full record

ArticlePloS one2022

Preconception risk factors and health care needs of pregnancy-planning women and men with a lifetime history or current mental illness: A nationwide survey.

Cindy-Lee Dennis, Hilary K Brown, Sarah Brennenstuhl, Simone Vigod, Ainsley Miller, Rita Amiel Castro, Flavia Casasanta Marini, Catherine Birken

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cindy-Lee DennisLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-0135-7242
Hilary K BrownInterdisciplinary Centre for Health & Society, University of Toronto Scarborough, Toronto, Ontario, Canada.
Sarah BrennenstuhlLawrence S. Bloomberg Faculty of Nursing, University of Toronto, Toronto, Ontario, Canada.
Simone VigodDepartment of Psychiatry, University of Toronto, Toronto, Ontario, Canada.
Ainsley MillerSchool of Nursing, Lakehead University, Thunder Bay, Ontario, Canada.
Rita Amiel CastroDepartment of Psychology, University of Zurich, Zurich, Germany.ORCID 0000-0002-4951-8770
Flavia Casasanta MariniLi Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Catherine BirkenDepartment of Pediatrics, University of Toronto, Toronto, Ontario, Canada.

Funding

CIHR HLC-154502
6 · The paper itself

Abstract

objectivesWhile depression and anxiety are common in women and men of reproductive age, preconception interventions to optimize the health of individuals with mental illness before pregnancy is limited and focuses primarily on psychotropic medication management. Comparing individuals with depression, anxiety, and comorbidity to those with neither condition, we identified areas of preconception care optimization related to psychosocial risk factors, general physical health, medication use, and uptake of high-risk health behaviours. We also investigated differences in preconception health care use, attitudes, and knowledge.

methodWe conducted a nationwide survey of 621 women (n = 529) and men (n = 92) across Canada who were planning a pregnancy within five years, including those with lifetime or current depression (n = 38), anxiety (n = 55), and comorbidity (n = 104) and those without mental illness (n = 413). Individuals with depression, anxiety, and comorbidity were compared to individuals without mental illness using logistic regression, adjusted for age, sex, and education level.

resultsIndividuals with a lifetime or current mental illness were significantly more likely to have several risk factors for suboptimal reproductive and perinatal outcomes, including increased rates of obesity, stress, fatigue, loneliness, number of chronic health conditions, and medication use. Further, they were more likely to have high-risk health behaviours including increased substance use, internet addiction, poorer eating habits, and decreased physical activity. By assessing depression, anxiety, or both separately, we also determined there was variation in risk factors by mental illness type.

conclusionOur nationwide study is one of the first and largest to examine the preconception care needs of women and men with a lifetime or current mental illness who are pregnancy-planning. We found this population has many important reproductive and perinatal risk factors that are modifiable via preconception interventions which could have a significant positive impact on their health trajectories and those of their future children.

Indexed as

Mental DisordersAnxiety DisordersChildChronic DiseaseDelivery of Health CareFemaleHumansMalePreconception CarePregnancyRisk Factors

Identifiers

PMID35731809
PMCPMC9216596

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.