ArticleNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2022
Outcomes of incident patients treated with incremental haemodialysis as compared with standard haemodialysis and peritoneal dialysis.
Article in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Peritoneal dialysis versus haemodialysis for people commencing dialysis.The Cochrane database of systematic reviews · 2024Pooled it
- Impact of incremental initiation of haemodialysis on mortality: a systematic review and meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Pooled it
- Characterization of residual kidney function in chronic hemodialysis patients using plasma metabolomics.Scientific reports · 2026Article
- Incremental vs. standard hemodialysis for preserving residual kidney function: a case-control study.BMC nephrology · 2025Observational
- Secular trends of bloodstream infections in hemodialysis patients: insights from a longitudinal Swiss study.Antimicrobial resistance and infection control · 2025Article
- Mortality associated with the COVID-19 pandemic in the Swiss dialysis population beyond SARS-CoV-2 infection.Clinical kidney journal · 2024Article
- Incremental hemodialysis and vascular access complications: a 12-year experience in a hospital hemodialysis unit.Journal of nephrology · 2024Article
- Incremental dialysis: two complementary views.Clinical kidney journal · 2024Article
- Incremental dialysis: review of the literature with pediatric perspective.Pediatric nephrology (Berlin, Germany) · 2024Review
- Incremental versus conventional haemodialysis in end-stage kidney disease: a systematic review and meta-analysis.Clinical kidney journal · 2024Article
- Home dialysis in older adults: challenges and solutions.Clinical kidney journal · 2023Article
- Australian Workshops on Patients' Perspectives on Hemodialysis and Incremental Start.Kidney international reports · 2023Article
- Position Statement of the Brazilian Society of Nephrology on incremental dialysis.Jornal brasileiro de nefrologiaArticle
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundResidual kidney function is considered better preserved with incremental haemodialysis (I-HD) or peritoneal dialysis (PD) as compared with conventional thrice-weekly HD (TW-HD) and is associated with improved survival. We aimed to describe outcomes of patients initiating dialysis with I-HD, TW-HD or PD.
methodsWe conducted a retrospective analysis of a prospectively assembled cohort in a single university centre including all adults initiating dialysis from January 2013 to December 2020. Primary and secondary endpoints were overall survival and hospitalization days at 1 year, respectively.
resultsWe included 313 patients with 234 starting on HD (166 TW-HD and 68 I-HD) and 79 on PD. At the end of the study, 10 were still on I-HD while 45 transitioned to TW-HD after a mean duration of 9.8 ± 9.1 months. Patients who stayed on I-HD were less frequently diabetics (P = .007). Mean follow-up was 33.1 ± 30.8 months during which 124 (39.6%) patients died. Compared with patients on TW-HD, those on I-HD had improved survival (hazard ratio 0.49, 95% confidence interval 0.26-0.93, P = .029), while those on PD had similar survival. Initial kidney replacement therapy modality was not significantly associated with hospitalization days at 1 year.
conclusionsI-HD is suitable for selected patients starting dialysis and can be maintained for a significant amount of time before transition to TW-HD, with diabetes being a risk factor. Although hospitalization days at 1 year are similar, initiation with I-HD is associated with improved survival as compared with TW-HD or PD. Results of randomized controlled trials are awaited prior to large-scale implementation of I-HD programmes.
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