Evidence map›Paper›PMID 35731511›Full record

ArticleInvestigative ophthalmology & visual science2022

Characteristics of the Optic Nerve Head in Myopic Eyes Using Swept-Source Optical Coherence Tomography.

Dan Cheng, Kaiming Ruan, Minhui Wu, Yilin Qiao, Weiqian Gao, Hengli Lian, Meixiao Shen, Fangjun Bao, Yizeng Yang, Jun Zhu and 4 more

Open access · goldAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 40 citations in OpenAlex.

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  14. Implications of optic disc rotation in the visual field progression of myopic open-angle glaucoma.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Dan ChengThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Kaiming RuanThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Minhui WuThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Yilin QiaoThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Weiqian GaoThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Hengli LianThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Meixiao ShenThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Fangjun BaoThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Yizeng YangThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Jun ZhuThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Haiying HuangThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Xianwei MengThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Lijun ShenThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Yufeng YeThe Affiliated Eye Hospital of Wenzhou Medical University, Hangzhou, Zhejiang, China.
Affiliated Eye Hospital of Wenzhou Medical College · CNWenzhou Medical University · CNZhejiang Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the characteristics of the optic nerve head (ONH) in myopia using swept-source optical coherence tomography (SS-OCT). Methods: Participants were divided into three groups according to the axial length (AL). The optic disc morphology, retinal nerve fiber layer (RNFL) thickness, and radial peripapillary capillary (RPC) vessel density (VD), optic disc tilt, rotation, Bruch's membrane opening distance (BMOD), border length (BL), border tissue angle, focal lamina cribrosa (LC) defects, β- and γ-zone peripapillary atrophy (PPA), microvasculature dropout (MvD), choroidal thickness (CT), and the choroidal vascularity index (CVI) were compared. Linear regression analysis evaluated relationships between spherical equivalent, AL, and ONH parameters. Results: One hundred five, 98, and 118 eyes were included in groups 1, 2, and 3, respectively. With AL increasing, the mean, superior and temporal CT, central mean and temporal, pericentral mean, inferior and nasal RPC VD, and temporal CVI decreased, whereas the mean and temporal RNFL thickness, optic disc, RIM and β-PPA area, presence and area of γ-PPA, BMOD and BL increased. Compared to other groups, group 3 depicted a larger cup area, more focal LC defect and total and juxtapapillary MvD; a lower central superior, inferior and nasal, pericentral superior, and temporal RPC VD. Group 1 demonstrated more tilted disc, larger inferior and nasal CT, mean, superior, inferior, and nasal CVI. Conclusions: Myopia eyes have larger ONH changes, PPAs, regional RNFL, and MvD, but smaller regional CTs, RPC VD, and CVIs. SS-OCT may be useful in detecting ONH variations during myopia.

Indexed as

MyopiaOptic DiskBruch MembraneHumansRetinal Ganglion CellsTomography, Optical Coherence

Identifiers

PMID35731511
PMCPMC9233286
OpenAlexW4283327801

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.