ArticleJournal of fluorescence2022
The Development of a 4-aminonaphthalimide-based Highly Selective Fluorescent Probe for Rapid Detection of HOCl.
Article in Journal of fluorescence, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- A "Turn-on" Fluorescent Probe Based on Phenothiazine for Selectively Recognizing ClOJournal of fluorescence · 2023Article
- A New and Fast-Response Fluorescent Probe for Monitoring Hypochlorous Acid Derived from Myeloperoxidase.Molecules (Basel, Switzerland) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, more and more evidence indicated that intracellular HOCl plays a crucial role in the regulation of inflammation and apoptosis, while excessive HOCl has an impact on human health problems. So, the development of methods for sensitive detection of HOCl is very vital to reveal its various physiological and pathological functions. In this paper, we have described a simple fluorescent probe for selective detection of HOCl, whereas for higher concentrations of other biological important substances, the probe almost does not respond. The experimental results show that the probe can quantitatively determine the range of 0-1 μM HOCl, the detection limit is 0.05 μM. In addition, the probe reacts quickly with HOCl (< 3 s), which is helpful to monitor HOCl in biological system because HOCl is highly reactive and short-lived. The ability of the probe to HOCl enables it to be used to track the HOCl levels in living systems.
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Registered trials
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