ArticleDigestive diseases and sciences2023
High Triglyceride-Glucose Index Is Associated with Poor Prognosis in Patients with Acute Pancreatitis.
Article in Digestive diseases and sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 26 citations in OpenAlex.
- A prognostic model based on integrated clinical indicators for recurrent acute pancreatitis in patients with hypertriglyceridemia: a retrospective cohort study.Lipids in health and disease · 2026Article
- Article
- Prognostic analysis of acute pancreatitis due to different etiologies and establishment and validation of an early prediction model.Lipids in health and disease · 2026Article
- Insulin resistance-related surrogate indices and recurrence of mild hypertriglyceridemic acute pancreatitis: a retrospective cohort study.Frontiers in nutrition · 2026Article
- Article
- Construction of a nomogram for hypertriglyceridemic severe acute pancreatitis that includes metabolic indexes.Lipids in health and disease · 2025Article
- The prognostic value of the triglyceride-glucose index in predicting recurrence of acute pancreatitis: a retrospective cohort study.Nutrition & metabolism · 2025Article
- Review
- Association between the triglyceride glucose index and the risk of acute respiratory failure in patients with acute pancreatitis.BMC gastroenterology · 2025Article
- Association between the development of sepsis and the triglyceride-glucose index in acute pancreatitis patients: a retrospective investigation utilizing the MIMIC-IV database.BMC gastroenterology · 2025Article
- Association between the triglyceride-glucose index and the risk of acute kidney injury in critically ill patients with acute pancreatitis: a retrospective study.Journal of intensive care · 2025Article
- Triglyceride glucose index and mortality in tracheally intubated patients: a MIMIC-IV retrospective cohort study.PloS one · 2025Article
- Triglyceride-glucose index as a key predictor of ARDS in acute pancreatitis: SHAP analysis reveals its critical role in risk stratification.Frontiers in nutrition · 2025Article
- Analysis of factors influencing onset and survival of patients with severe acute pancreatitis: A clinical study.Immunity, inflammation and disease · 2024Article
- Triglyceride-Glucose Index is an Independent Risk Factor for Hepatocellular Carcinoma Development in Patients with HBV-Related Liver Cirrhosis.Journal of hepatocellular carcinoma · 2024Article
- Pheochromocytoma Multisystem Crisis Complicated by Severe Acute Pancreatitis.Internal medicine (Tokyo, Japan) · 2023Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute pancreatitis (AP) is a common gastrointestinal disease worldwide. Severe acute pancreatitis (SAP) is characterized as persistent organ failure with a mortality rate as high as 20-30%. Early assessment of the severity and screening out possible SAP is of great significance. Given that there is still a lack of both convenient and practical tools for evaluating SAP, we conducted this study to explore the association between TyG index and acute pancreatitis prognosis.
methodsA total of 353 in-patients diagnosed with acute pancreatitis in the Second Hospital of Shandong University were retrospectively enrolled from January 2018 to November 2021 in this study. According to the Atlanta Classification, they were divided into two groups based on the AP severity. Demographic information and clinical materials were retrospectively collected. The TyG index calculation formula is as follows: ln [fasting triglycerides (mg/dL) × fasting plasma glucose (mg/dL)/2]. Statistical analyses were performed using SPSS software (IBM version 22.0) and Medcalc software. Multivariable logistic regression analyses were used to investigate independent predictors for SAP. ROC curve was plotted to assess the predictive ability and cutoffs of TyG index.
resultsA total of 353 AP patients were respectively enrolled in this study, of which 47 suffered from SAP. Compared with the non-SAP group, TyG index was significantly higher in the SAP group (10.44 ± 1.55 vs 9.33 ± 1.44, P < 0.001). Multivariate logistic regression analysis showed that TyG index was an independent risk factor for SAP (OR 1.835, 95% CI 1.380-2.442 P < 0.001), with a cutoff of 8.76 for non-HTG/AAP and 11.81 for HTG/AAP by ROC curve. TyG index of patients who suffered from SIRS, OF, APFC, and ANC was higher than those without (P < 0.05).
conclusionsThe triglyceride-glucose index is an independent risk factor for SAP. High TyG index is closely related to SAP and AP-related complications.
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