ArticleClinical oral investigations2022
Efficacy of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) in late adolescents and adults with the Dutch Maxillary Expansion Device: a prospective clinical cohort study.
Article in Clinical oral investigations, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Ultrasonic-assisted minimally invasive sarpe and mandibular skeletal anchorage for treatment of class III dentofacial anomalies: a non-endoscopic, minimally invasive approach - systematic review and case series of 10 patients.Oral and maxillofacial surgery · 2026Pooled it
- Tissue-Specific Remodeling and Load Partitioning in Maxillary Expansion: An Evidence-Informed Three-Compartment Mechanobiological Framework.Bioengineering (Basel, Switzerland) · 2026Article
- Bone-Screw-Force Interactions in Palatal Orthodontic Mini-Implants: A Scoping Review and Decision Framework for Primary Stability and Biomechanically Driven Site Selection.Journal of functional biomaterials · 2026Review
- Bone Remodeling by Rapid Maxillary Expansion (RME): Evidence from the Monitoring of Bone Turnover Biomarkers in Salivary Matrix.Dentistry journal · 2026Article
- Diagnostic Assessment of Periodontal and Dentoalveolar Complications Following Mini-Screw-Assisted Rapid Palatal Expansion in Adults and Late Adolescents: A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- Evaluation of palatal bone thickness and palatal depth angle for optimal mini-implant placement in MARPE: A CBCT study.Journal of orthodontic science · 2026Article
- Review
- Review
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- Maxillary Bone Fracture Due to a Miniscrew-Assisted Rapid Maxillary Expansion: A Case Report.Journal of clinical medicine · 2025Article
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- Comparison of Side Effects Between Miniscrew-Assisted Rapid Palatal Expansion (MARPE) and Surgically Assisted Rapid Palatal Expansion (SARPE) in Adult Patients: A Scoping Review.Dentistry journal · 2025Review
- Stability of expansion effects following Miniscrew-assisted Rapid Palatal expansion: a prospective longitudinal cohort study.Oral and maxillofacial surgery · 2025Article
- A new removable connecting device for MARPE expander with non-common path of insertion.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024Article
- Impact of digital orthodontics on maxillary protraction with implants in children with skeletal class III: A systematic review and meta-analysis.The Saudi dental journal · 2024Review
- Influence of miniscrew-assisted rapid palatal expansion (MARPE) on the interdental papilla height of maxillary central incisors.Clinical oral investigations · 2023Article
- What is the impact of miniscrew-assisted rapid palatal expansion on the midfacial soft tissues? A prospective three-dimensional stereophotogrammetry study.Clinical oral investigations · 2023Article
- What is the Oral Health-related Quality of Life following Miniscrew-Assisted Rapid Palatal Expansion (MARPE)? A prospective clinical cohort study.BMC oral health · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo provide a higher degree of evidence on the efficacy of Miniscrew-Assisted Rapid Palatal Expansion (MARPE) in late adolescents and adults, thereby applying the Dutch Maxillary Expansion Device (D-MED). MATERIALS AND
methodsD-MED was developed as an individualized, 3D-designed, and fabricated MARPE appliance supported by 4 palatal miniscrews. Patients from the age of 16 onwards with transverse maxillary deficiency were enrolled consecutively. Pre-expansion and immediate post-expansion CBCTs and intra-oral scans were acquired and measurements of skeletal, alveolar, and dental expansion as well as dental and periodontal side-effects were performed.
resultsThirty-four patients were enrolled (8 men, 26 women) with mean age 27.0 ± 9.4 years. A success rate of 94.1% was achieved (32/34 patients). The mean expansion duration, or mean observation time, was 31.7 ± 8.0 days. The mean expansion at the maxillary first molars (M1) and first premolars (P1) was 6.56 ± 1.70 mm and 4.19 ± 1.29 mm, respectively. The expansion was 60.4 ± 20.1% skeletal, 8.1 ± 27.6% alveolar, and 31.6 ± 20.1% dental at M1 and 92.2 ± 14.5% skeletal, 0.0 ± 18.6% alveolar, and 7.8 ± 17.7% dental at P1, which was both statistically (p < 0.001) and clinically significant. Buccal dental tipping (3.88 ± 3.92° M1; 2.29 ± 3.89° P1), clinical crown height increase (0.12 ± 0.31 mm M1; 0.04 ± 0.22 mm P1), and buccal bone thinning (- 0.31 ± 0.49 mm M1; - 0.01 ± 0.45 mm P1) were observed, while root resorption could not be evaluated.
conclusionsMARPE by application of D-MED manifested its efficacy in a prospective clinical setting, delivering a high amount of skeletal expansion with limited side-effects in late adolescents and adults. CLINICAL RELEVANCE: Higher quality evidence is supportive of MARPE as a safe and successful non-surgical treatment option for transverse maxillary deficiency.
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