Evidence map›Paper›PMID 35731170›Full record

ArticleEmerging infectious diseases2022

Novel Mycobacterium tuberculosis Complex Genotype Related to M. caprae.

Joseph Shea, Carol Smith, Tanya A Halse, Donna Kohlerschmidt, Amy K Rourke, Kimberlee A Musser, Vincent Escuyer, Pascal Lapierre

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Predicting isoniazid resistance inJournal of clinical microbiology · 2026
    Article
  2. Article
  3. Article
  4. Natural outbreak ofJournal of toxicologic pathology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joseph Shea
Carol Smith
Tanya A Halse
Donna Kohlerschmidt
Amy K Rourke
Kimberlee A Musser
Vincent Escuyer
Pascal Lapierre

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the unusual genotypic characterization of a bacterium isolated from a clinical sample of a patient who grew up in Bangladesh and lives in the United States. Using whole-genome sequencing, we identified the bacterium as a member of the Mycobacterium tuberculosis complex (MTBC). Phylogenetic placement of this strain suggests a new MTBC genotype. Even though it had the same spoligotype as M. caprae strains, single-nucleotide polymorphism-based phylogenetic analysis placed the isolate as a sister lineage distinct from M. caprae, most closely related to 5 previously sequenced genomes isolated from primates and elephants in Asia. We propose a new animal-associated lineage, La4, within MTBC.

Indexed as

Mycobacterium tuberculosisAnimalsBangladeshGenotypeHumansPhylogenyWhole Genome Sequencinganimal-adaptedbacteriagenotypesMTBC lineagesMycobacterium tuberculosisMycobacterium tuberculosis complextuberculosis and other mycobacteriaUnited States

Identifiers

PMID35731170
PMCPMC9239888

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.