Evidence map›Paper›PMID 35731007›Full record

ArticleACS nano2022

Tuning Protein Hydrogel Mechanics through Modulation of Nanoscale Unfolding and Entanglement in Postgelation Relaxation.

Matt D G Hughes, Sophie Cussons, Najet Mahmoudi, David J Brockwell, Lorna Dougan

Open access · hybridAbstract read
In one paragraph

Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. HGels (Basel, Switzerland) · 2025
    Article
  4. Review
  5. Article
  6. Capturing Dynamic Assembly of Nanoscale Proteins During Network Formation.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Matt D G HughesSchool of Physics and Astronomy, Faculty of Engineering and Physical Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0001-5838-7939
Sophie CussonsAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, U.K.
Najet MahmoudiISIS Neutron and Muon Spallation Source, STFC Rutherford Appleton Laboratory, Oxfordshire OX11 0QX, U.K.
David J BrockwellAstbury Centre for Structural Molecular Biology, University of Leeds, Leeds LS2 9JT, U.K.
Lorna DouganSchool of Physics and Astronomy, Faculty of Engineering and Physical Sciences, University of Leeds, Leeds LS2 9JT, U.K.ORCID 0000-0002-2620-5827
University of Leeds · GBRutherford Appleton Laboratory · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Globular folded proteins are versatile nanoscale building blocks to create biomaterials with mechanical robustness and inherent biological functionality due to their specific and well-defined folded structures. Modulating the nanoscale unfolding of protein building blocks during network formation (

Indexed as

Biocompatible MaterialsHydrogelsProteinsProtein UnfoldingRheologyBiocompatible MaterialsHydrogelsProteinsbioinspiredbiomimeticchemical responsive hydrogelentanglementprotein-hydrogelprotein unfoldingrheology

Identifiers

PMID35731007
PMCPMC9331141
OpenAlexW4283323057

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.