Evidence map›Paper›PMID 35730931›Full record

ArticleeLife2022

Perceptual restoration fails to recover unconscious processing for smooth eye movements after occipital stroke.

Sunwoo Kwon, Berkeley K Fahrenthold, Matthew R Cavanaugh, Krystel R Huxlin, Jude F Mitchell

Open access · goldAbstract read
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sunwoo KwonHerbert Wertheim School of Optometry and Vision Science, University of California, Berkeley, Berkeley, United States.ORCID https://orcid.org/0000-0002-5761-6629
Berkeley K FahrentholdCenter for Visual Science, University of Rochester, Rochester, United States.
Matthew R CavanaughCenter for Visual Science, University of Rochester, Rochester, United States.
Krystel R Huxlin *Department of Brain and Cognitive Sciences, University of Rochester, Rochester, United States.ORCID https://orcid.org/0000-0001-7138-6156
Jude F Mitchell *Department of Brain and Cognitive Sciences, University of Rochester, Rochester, United States.ORCID https://orcid.org/0000-0003-0197-7545
Center for Visual Communication (United States) · US

Funding

VISUAL SCIENCE RESEARCH CTR SUPPORTP30EY001319 · NEI · UNIVERSITY OF ROCHESTER · PI MICHELE RUCCI · 1985 to 2026
$17.5M
VISUAL SCIENCET32EY007125 · NEI · UNIVERSITY OF ROCHESTER · PI Krystel R Huxlin, Duje Tadin · 1990 to 2026
$7.1M
Vision recovery in cortical blindnessR01EY027314 · NEI · UNIVERSITY OF ROCHESTER · PI MARISA CARRASCO, Krystel R Huxlin · 2017 to 2026
$5.3M
Neural basis of trans-saccadic perceptionR01EY030998 · NEI · UNIVERSITY OF ROCHESTER · PI MITCHELL, JUDE F · 2020 to 2024
$1.9M
Mechanisms of visual learning in cortical blindnessR01EY021209 · NEI · UNIVERSITY OF ROCHESTER · PI HUXLIN, KRYSTEL R · 2011 to 2014
$1.5M
NEI NIH HHS P30 EY001319NEI NIH HHS R01 EY021209NEI NIH HHS R01 EY027314NEI NIH HHS R01 EY030998NEI NIH HHS T32 EY007125
6 · The paper itself

Abstract

The visual pathways that guide actions do not necessarily mediate conscious perception. Patients with primary visual cortex (V1) damage lose conscious perception but often retain unconscious abilities (e.g. blindsight). Here, we asked if saccade accuracy and post-saccadic following responses (PFRs) that automatically track target motion upon saccade landing are retained when conscious perception is lost. We contrasted these behaviors in the blind and intact fields of 11 chronic V1-stroke patients, and in 8 visually intact controls. Saccade accuracy was relatively normal in all cases. Stroke patients also had normal PFR in their intact fields, but no PFR in their blind fields. Thus, V1 damage did not spare the unconscious visual processing necessary for automatic, post-saccadic smooth eye movements. Importantly, visual training that recovered motion perception in the blind field did not restore the PFR, suggesting a clear dissociation between pathways mediating perceptual restoration and automatic actions in the V1-damaged visual system.

Indexed as

Motion PerceptionStrokeVisual CortexBlindnessEye MovementsHumansPhotic StimulationUnconsciousnessVisual PathwaysVisual Perceptioneye movementshemianopiahumanmotion processingneuroscienceoccipital strokepre-saccadic attentionvision restoration

Identifiers

PMID35730931
PMCPMC9255960
OpenAlexW4283320425

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.