Evidence map›Paper›PMID 35730924›Full record

ArticleeLife2022

A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions.

Aleksandr Alekseev, Georgii Pobegalov, Natalia Morozova, Alexey Vedyaykin, Galina Cherevatenko, Alexander Yakimov, Dmitry Baitin, Mikhail Khodorkovskii

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  3. Article
  4. Review
  5. Codeine dysregulates ribosome biogenesis inFuture drug discovery · 2023
    Article
  6. Proteomic Characterization of Virulence Factors and Related Proteins inInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Aleksandr Alekseev *Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.ORCID 0000-0003-4371-265X
Georgii Pobegalov *Peter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.ORCID 0000-0003-0836-0732
Natalia MorozovaPeter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.
Alexey VedyaykinPeter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.
Galina CherevatenkoPeter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.
Alexander YakimovPeter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.
Dmitry BaitinPetersburg Nuclear Physics Institute Named by B.P. Konstantinov of National Research Center «Kurchatov Institute», Gatchina, Russian Federation.
Mikhail KhodorkovskiiPeter the Great St. Petersburg Polytechnic University, St. Petersburg, Russian Federation.
Peter the Great St. Petersburg Polytechnic University · RUPetersburg Nuclear Physics Institute · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

RecA protein mediates homologous recombination repair in bacteria through assembly of long helical filaments on ssDNA in an ATP-dependent manner. RecX, an important negative regulator of RecA, is known to inhibit RecA activity by stimulating the disassembly of RecA nucleoprotein filaments. Here we use a single-molecule approach to address the regulation of (

Indexed as

Escherichia coliEscherichia coli ProteinsBacterial ProteinsDNA, Single-StrandedRec A RecombinasesBacterial ProteinsDNA, Single-StrandedEscherichia coli ProteinsRec A RecombinasesDNA repairE. colihomologous recombinationmolecular biophysicsRecARecXsingle-molecule approachSOS responsestructural biology

Identifiers

PMID35730924
PMCPMC9252578
OpenAlexW4283258945

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.