Evidence map›Paper›PMID 35730627›Full record

ArticleInternational journal of molecular medicine2022

Silencing of circular RNA‑ZYG11B exerts a neuroprotective effect against retinal neurodegeneration.

Cong Ma, Mu-Di Yao, Xiao-Yan Han, Ze-Hui Shi, Biao Yan, Jian-Ling Du

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Cong MaDepartment of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.
Mu-Di YaoEye Institute, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200030, P.R. China.
Xiao-Yan HanEye Institute, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200030, P.R. China.
Ze-Hui ShiEye Institute, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200030, P.R. China.
Biao YanEye Institute, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200030, P.R. China.
Jian-Ling DuDepartment of Endocrinology, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116011, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic retinal diseases are the major cause of vision impairment worldwide. Currently, there are no available treatments for ischemia‑induced retinal neurodegeneration. Circular RNAs (circRNAs) have emerged as important regulators of several biological processes and human diseases. The present study investigated the role of circRNA‑ZYG11B (circZYG11B; hsa_circ_0003739) in retinal neurodegeneration. Reverse transcription quantitative polymerase chain reaction (RT‑qPCR) demonstrated that circZYG11B expression was markedly increased during retinal neurodegeneration

Indexed as

MicroRNAsNeuroprotective AgentsRetinal DiseasesHumansIschemiaRetinaRNA, CircularMicroRNAsMIRN620 microRNA, humanNeuroprotective AgentsRNA, Circularcircular RNAischemia/reperfusionretinal ischemiaretinal neurodegeneration

Identifiers

PMID35730627
PMCPMC9239035

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.