Evidence map›Paper›PMID 35730587›Full record

ArticleACS synthetic biology2022

Efficient CRISPR/Cas12a-Based Genome-Editing Toolbox for Metabolic Engineering in

Jichen Bao, Enrique de Dios Mateos, Silvan Scheller

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Valine overproduction inMetabolic engineering communications · 2026
    Article
  4. Massive Cultivation ofACS omega · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. A promoter-RBS library for fine-tuning gene expression inApplied and environmental microbiology · 2024
    Article
  14. Article
  15. Teaching old dogs new tricks: genetic engineering methanogens.Applied and environmental microbiology · 2024
    Review
  16. Mechanisms of microbial co-aggregation in mixed anaerobic cultures.Applied microbiology and biotechnology · 2024
    Review
  17. Review
  18. Review
  19. Article
  20. CRISPR/Cas12a toolbox for genome editing inFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jichen BaoDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, FI-02150 Espoo, Finland.
Enrique de Dios MateosDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, FI-02150 Espoo, Finland.
Silvan SchellerDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, FI-02150 Espoo, Finland.ORCID 0000-0002-0667-9224
Aalto University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid-growing and genetically tractable methanogen

Indexed as

Gene EditingMethanococcusCarbon DioxideCRISPR-Cas SystemsHydrogenMetabolic EngineeringCarbon DioxideHydrogenCRISPR/Cas12agenome editingmetabolic engineeringMethanococcus maripaludismethanogenssynthetic biology

Identifiers

PMID35730587
PMCPMC9295151
OpenAlexW4283264202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.