Evidence map›Paper›PMID 35729767›Full record

ArticlePalliative medicine2022

Exploring the prevalence, impact and experience of cardiac cachexia in patients with advanced heart failure and their caregivers: A sequential phased study.

Matthew A Carson, Joanne Reid, Loreena Hill, Lana Dixon, Patrick Donnelly, Paul Slater, Alyson Hill, Susan E Piper, Theresa A McDonagh, Donna Fitzsimons

Abstract read
In one paragraph

Article in Palliative medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. The lived experience of renal cachexia: An interpretive phenomenological analysis.International journal of nursing studies advances · 2024
    Article
  6. Observational
  7. Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Matthew A CarsonSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.ORCID 0000-0003-2733-939X
Joanne ReidSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-5820-862X
Loreena HillSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.ORCID 0000-0001-5232-0936
Lana DixonRoyal Victoria Hospital, Belfast Health and Social Care Trust, Belfast, UK.
Patrick DonnellyUlster Hospital, South Eastern Health and Social Care Trust, Belfast, UK.
Paul SlaterInstitute of Nursing and Health Research, Ulster University, Belfast, UK.
Alyson HillNutrition Innovation Centre for Food and Health, Ulster University, Belfast, UK.
Susan E PiperDepartment of Cardiovascular Research, King's College London, James Black Centre, London, UK.
Theresa A McDonaghDepartment of Cardiovascular Research, King's College London, James Black Centre, London, UK.
Donna FitzsimonsSchool of Nursing and Midwifery, Queen's University Belfast, Belfast, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiac Cachexia is a wasting syndrome that has a significant impact on patient mortality and quality of life world-wide, although it is poorly understood in clinical practice.

aimIdentify the prevalence of cardiac cachexia in patients with advanced New York Heart Association (NYHA) functional class and explore its impact on patients and caregivers.

designAn exploratory cross-sectional study. The sequential approach had two phases, with phase 1 including 200 patients with NYHA III-IV heart failure assessed for characteristics of cardiac cachexia. Phase 2 focussed on semi-structured interviews with eight cachectic patients and five caregivers to ascertain the impact of the syndrome. SETTING/

participantsTwo healthcare trusts within the United Kingdom.

resultsCardiac Cachexia was identified in 30 out of 200 participants, giving a prevalence rate of 15%. People with cachexia had a significantly reduced average weight and anthropometric measures (

conclusionsCardiac cachexia has a debilitating effect on patients and caregivers. Future work should focus on establishing a specific definition and clinical pathway to enhance patient and caregiver support.

Indexed as

CachexiaHeart FailureCaregiversCross-Sectional StudiesHumansPrevalenceQuality of LifeCachexiacaregiverheart failureprevalencequalitativequantitativesequential phased

Identifiers

PMID35729767
PMCPMC9248000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.