ArticleScientific reports2022
Measuring collagen injury depth for burn severity determination using polarization sensitive optical coherence tomography.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Two-step regression analysis approach to assess burn wound severity using spatial frequency domain imaging.Journal of biomedical optics · 2026Article
- Non-invasive Resonance Raman Spectroscopy provides an early estimation of depth in a pig model of multi-depth burns.Journal of translational medicine · 2025Article
- Optical phenotyping using label-free microscopy and deep learning.Biophotonics discovery · 2025Article
- PS-OCT imaging of the anterior segment under different eyeball rotations.Biomedical optics express · 2025Article
- 3D-cell phantom-experimental setup to assess thermal effects and cell viability of lung tumor cells after electroporation.Scientific reports · 2024Article
- Visualization enhancement by PCA-based image fusion for skin burns assessment in polarization-sensitive OCT.Biomedical optics express · 2024Article
- Depth of intact vascular plexus - visualized with optical coherence tomography - correlates to burn depth in thoracic thermic injuries in children.Innovative surgical sciences · 2024Article
- Mapping optical scattering properties to physical particle information in singly and multiply scattering samples.Biomedical optics express · 2023Article
- Advances in non-invasive biosensing measures to monitor wound healing progression.Frontiers in bioengineering and biotechnology · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Determining the optimal treatment course for a dermatologic burn wound requires knowledge of the wound's severity, as quantified by the depth of thermal damage. In current clinical practice, burn depth is inferred based exclusively on superficial visual assessment, a method which is subject to substantial error rates in the classification of partial thickness (second degree) burns. Here, we present methods for direct, quantitative determination of the depth extent of injury to the dermal collagen matrix using polarization-sensitive optical coherence tomography (PS-OCT). By visualizing the depth-dependence of the degree of polarization of light in the tissue, rather than cumulative retardation, we enable direct and volumetric assessment of local collagen status. We further augment our PS-OCT measurements by visualizing adnexal structures such as hair follicles to relay overall dermal viability in the wounded region. Our methods, which we have validated ex vivo with matched histology, offer an information-rich tool for precise interrogation of burn wound severity and healing potential in both research and clinical settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.