Evidence map›Paper›PMID 35729170›Full record

ArticleScientific reports2022

COVID-19 associated mucormycosis in Assiut University Hospitals: a multidisciplinary dilemma.

Sahar Farghly Youssif, Marwa M Abdelrady, Ahmed Atef Thabet, Mohamed A Abdelhamed, Mohamed Omar A Gad, Ahmed Mohmmed Abu-Elfatth, Ghada Mohamed Saied, Islam Goda, Abdelazeem M Algammal, Gaber El-Saber Batiha and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 25 citations in OpenAlex.

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  5. Dependability and Prognostic Value of Biomarkers in COVID-19 Associated Rhino-Orbito- Cerebral Mucormycosis- A Long Term Ambispective Study.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Sahar Farghly YoussifDepartment of Chest Disease and Tuberculosis, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Marwa M AbdelradyDepartment of Anesthesia and Critical Care, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Ahmed Atef ThabetDepartment of Internal Medicine and Critical Care, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Mohamed A AbdelhamedDepartment of Neurology and Psychiatry, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Mohamed Omar A GadDepartment of Otorhinolaryngology, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Ahmed Mohmmed Abu-ElfatthDepartment of Tropical Medicine and Gastroenterology, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Ghada Mohamed SaiedDepartment of Clinical Pathology Department, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Islam GodaDepartment of Ophthalmology Department, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Abdelazeem M AlgammalDepartment of Bacteriology, Immunology and Mycology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, 41522, Egypt.
Gaber El-Saber BatihaDepartment of Pharmacology and Therapeutics, Faculty of Veterinary Medicines, Damanhour University, Damanhour, 22511, Egypt.
Nessren M Abd El-RadyMedical Physiology Department, Faculty of Medicine, Assiut University, Assiut, 71515, Egypt.
Helal F HettaDepartment of Medical Microbiology and Immunology, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt. helalhetta@aun.edu.eg.ORCID 0000-0001-8541-7304
Soheir M KasemDepartment of Internal Medicine and Critical Care, Faculty of Medicine, Assuit University, Assiut, 71515, Egypt.
Assiut University · EGDamanhour University · EGSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is a life-threatening opportunistic angioinvasive fungal infection. We aimed to describe the frequency, presentations, predictors, and in-hospital outcome of mucormycosis patients in the scope of CoronaVirusDisease-19 (COVID-19) during the third viral pandemic wave. This cross-sectional retrospective study included all patients who fulfilled the criteria of mucormycosis with concurrent confirmed covid19 infection admitted to Assuit University Hospital between March 2021 and July 2021. Overall, 433 patients with definite covid-19 infection, of which 33 (7.63%) participants were infected with mucormycosis. Mucormycosis was predominantly seen in males (21 vs. 12; p = 0.01). Diabetes mellitus (35% vs. 63.6%; p < 0.001), hypertension (2% vs.45.5%; p 0.04), and Smoking (26.5% vs. 54.5%; p < 0.001) were all significantly higher in mucormycosis patients. Inflammatory markers, especially E.S.R., were significantly higher in those with mucormycosis (p < 0.001). The dose of steroid intake was significantly higher among patients with mucormycosis (160 mg vs. 40 mg; p < 0.001). Except for only three patients alive by residual infection, 30 patients died. The majority (62%) of patients without mucormycosis were alive. Male sex; Steroid misuse; D.M.; Sustained inflammation; Severe infection were significant risk factors for mucormycosis by univariate analysis; however, D.M.; smoking and raised E.S.R. were predictors for attaining mucormycosis by multivariate analysis.

Indexed as

COVID-19MucormycosisCross-Sectional StudiesHospitals, UniversityHumansMaleRetrospective Studies

Identifiers

PMID35729170
PMCPMC9212202
OpenAlexW4283262681

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.