ArticleProceedings of the National Academy of Sciences of the United States of America2022
Collective behavior and nongenetic inheritance allow bacterial populations to adapt to changing environments.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Growth-dependent sensory bet-hedging enhances collective navigation.bioRxiv : the preprint server for biology · 2026Article
- Spatial structure: shaping the ecology and evolution of microbial communities.FEMS microbiology reviews · 2026Review
- Article
- Mixing of a binary passive particle system using smart active particles.Scientific reports · 2025Article
- ChemotaxingArXiv · 2025Article
- ChemotaxingbioRxiv : the preprint server for biology · 2025Article
- Self-generated chemotaxis of mixed cell populations.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Dual-purpose dynamics emerge from a heterogeneous cell population in Drosophila metamorphosis.PLoS computational biology · 2025Article
- Information and fitness in two-state systems: self-replicating individuals in a fluctuating environment.ArXiv · 2025Article
- Intermediate light adaptation induces oscillatory phototaxis switching and pattern formation inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- RABiTPy: an open-source Python software for rapid, AI-powered bacterial tracking and analysis.BMC bioinformatics · 2025Article
- Phenotype structuring in collective cell migration: a tutorial of mathematical models and methods.Journal of mathematical biology · 2025Review
- Evolutionary consequences of bacterial resistance to a flagellotropic phage.bioRxiv : the preprint server for biology · 2025Article
- Coarse-graining bacterial diffusion in disordered media to surface states.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Nongenetic adaptation by collective migration.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Navigated range expansion promotes migratory culling.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Reassessing the Standard Chemotaxis Framework for Understanding Biased Migration inAnnual review of chemical and biomolecular engineering · 2024Review
- Microfluidic approaches in microbial ecology.Lab on a chip · 2024Review
- Synchronous and Fully Steerable Active Particle Systems for Enhanced Mimicking of Collective Motion in Nature.Advanced materials (Deerfield Beach, Fla.) · 2024Article
- The ability to sense the environment is heterogeneously distributed in cell populations.eLife · 2024Article
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2 authors at 1 institution in 1 country.
Funding
Abstract
Collective behaviors require coordination among a group of individuals. As a result, individuals that are too phenotypically different from the rest of the group can be left out, reducing heterogeneity, but increasing coordination. If individuals also reproduce, the offspring can have different phenotypes from their parent(s). This raises the question of how these two opposing processes-loss of diversity by collective behaviors and generation of it through growth and inheritance-dynamically shape the phenotypic composition of an isogenic population. We examine this question theoretically using collective migration of chemotactic bacteria as a model system, where cells of different swimming phenotypes are better suited to navigate in different environments. We find that the differential loss of phenotypes caused by collective migration is environment-dependent. With cell growth, this differential loss enables migrating populations to dynamically adapt their phenotype compositions to the environment, enhancing migration through multiple environments. Which phenotypes are produced upon cell division depends on the level of nongenetic inheritance, and higher inheritance leads to larger composition adaptation and faster migration at steady state. However, this comes at the cost of slower responses to new environments. Due to this trade-off, there is an optimal level of inheritance that maximizes migration speed through changing environments, which enables a diverse population to outperform a nondiverse one. Growing populations might generally leverage the selection-like effects provided by collective behaviors to dynamically shape their own phenotype compositions, without mutations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.