ArticleJournal of assisted reproduction and genetics2022
Endometrial compaction is associated with increased clinical and ongoing pregnancy rates in unstimulated natural cycle frozen embryo transfers: a prospective cohort study.
Article in Journal of assisted reproduction and genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Can endometrial compaction predict live birth rates in assisted reproductive technology cycles? A systematic review and meta-analysis.Journal of assisted reproduction and genetics · 2023Pooled it
- Does endometrial compaction before embryo transfer affect pregnancy outcomes? a systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Comparison of the efficacy of letrozole-ovulation induction cycle, natural cycle, and hormonal replacement therapy cycle in cryopreserved embryo transfer: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- A New Method of Assessing Endometrial Compaction as an Indicator of Endometrial Receptivity for Predicting Reproductive Success.Journal of clinical medicine · 2025Article
- Effects of autologous platelet-rich plasma intrauterine perfusion on clinical outcomes in recurrent implantation failure patients with non-thin endometrium undergoing frozen-thawed embryo transfer.Archives of gynecology and obstetrics · 2025Article
- Investigating the Effect of Endometrial Thickness Changes and Compaction on the Fertility Rate of Patients Undergoing ART: A Prospective Study.Journal of obstetrics and gynaecology of India · 2025Article
- Endometrial Thickness Change in Response to Progesterone is Associated with Ongoing Pregnancy Rate in Women with Treated Intrauterine Adhesion - A Prospective Cohort Study.International journal of women's health · 2025Article
- Endometrial compaction shows no association with improved pregnancy outcomes in hormonal replacement frozen-thawed embryo transfer: an analysis of over 16 000 cases.Human reproduction open · 2025Article
- Endometrial compaction in patients with chronic endometritis does not predict pregnancy outcomes: a retrospective study.Frontiers in endocrinology · 2025Article
- Does Endometrial Thickness or Compaction Impact the Success of Frozen Embryo Transfer? A Cohort Study Analysis.Journal of clinical medicine · 2024Article
- Endometrial compaction to predict pregnancy outcomes in patients undergoing assisted reproductive technologies: a systematic review and meta-analysis.Human reproduction open · 2024Article
- Article
- Comparing the pregnancy outcomes of cleavage and blastocyst stage in frozen embryo transfer cycles: A cross-sectional study.International journal of reproductive biomedicine · 2023Article
- Preparation of the endometrium for frozen embryo transfer: an update on clinical practices.Reproductive biology and endocrinology : RB&E · 2023Review
- Impact of endometrial compaction on reproductive outcomes after cryotransfer of euploid embryos in a modified natural cycle: protocol for a prospective cohort study.Frontiers in endocrinology · 2023Article
- Endometrial thickness and early pregnancy complications after frozen-thawed embryo transfers.Frontiers in endocrinology · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the association between endometrial compaction and pregnancy rates in unstimulated natural cycle frozen embryo transfers.
designA single-center prospective cohort study. Endometrial thickness by transvaginal ultrasound and blood progesterone levels on the day of ovulation and the day of embryo transfer were evaluated in patients undergoing natural cycle frozen embryo transfer. Compaction was defined as > 5% decrease in endometrial thickness between ovulation day and day of transfer. Clinical and ongoing pregnancy rates in cycles with and without compaction were compared.
resultsSeventy-one women were included, of which 44% had endometrial compaction, with similar rates when subdividing the patients by day of transfer (day 3 or day 5). Clinical and ongoing pregnancy rates were higher in the compaction group compared to the non-compaction group (0.58 vs. 0.16, P < 0.001; 0.52 vs. 0.13, P < 0.001 respectively). Subdividing by degree of compaction > 10% and > 15% revealed similar pregnancy rates as > 5%, with no added benefit to higher degrees of compaction.
conclusionsAbout half the patients in our study undergoing unstimulated natural cycle frozen embryo transfer experienced compaction of the endometrium, occurring as early as day 3 post-ovulation. This was significantly correlated with increased clinical and ongoing pregnancy rates.
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