SynthesisEuropean radiology2022
Risk of acute kidney injury after contrast-enhanced computerized tomography: a systematic review and meta-analysis of 21 propensity score-matched cohort studies.
Synthesis in European radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 43 citations in OpenAlex.
- Effects of carnosic acid on renal injury-related parameters and iNOS immunoreactivity in an experimental model of contrast-associated acute kidney injury.Renal failure · 2026Article
- Early and delayed acute kidney injury after contrast-enhanced CT in critically ill adults: a target trial emulation.Emergency radiology · 2026Article
- Application of 50-keV virtual monochromatic imaging combined with a personalized contrast agent protocol in computed tomography pulmonary angiography: a randomized controlled trial.Quantitative imaging in medicine and surgery · 2026Article
- Contrast-Associated AKI in Hospitalized Adults With Sickle Cell Disease.Kidney international reports · 2026Article
- Age- and Sex-Related Patterns in Coronary CT Angiography Referrals and Coronary Atherosclerotic Burden: A Single-Center Real-World Referral-Based Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- CT of Soft Tissue Infections: Current and Future Perspectives from Diagnosis to Treatment.Journal of clinical medicine · 2026Review
- Safety and Feasibility of a CT-Based Pathway for Left Atrial Appendage Assessment Prior to Inpatient Cardioversion: A Single-Center Experience.Clinical cardiology · 2026Article
- Article
- The Incidence of Contrast-Induced Nephropathy Among Low-Risk Cancer Patients with Preserved Renal Function on Active Treatment Undergoing Contrast-Enhanced Computed Tomography: A Single-Site Experience.Healthcare (Basel, Switzerland) · 2026Article
- Development and validation of a clinical prediction model for postcontrast acute kidney injury in patients with postoperative acute kidney injury of acute Stanford type A aortic dissection.Frontiers in cardiovascular medicine · 2026Article
- Impact of contrast-induced acute kidney injury on patients with acute coronary syndrome: results of a prospective cohort.Frontiers in cardiovascular medicine · 2026Article
- Incidence and risk factors of acute kidney injury among neurocritical patients in high-altitude regions: a retrospective cohort study.Frontiers in medicine · 2026Article
- Incidence and risk factors of contrast-associated acute kidney injury in patients hospitalised after contrast-enhanced computed tomography in the emergency department.International journal of emergency medicine · 2025Article
- Gastrointestinal complications in intensive care.Medical review (2021) · 2025Review
- Comparative Evaluation of Clinical and Immunonutritional Risk Scores for Predicting Contrast-Associated Acute Kidney Injury in Emergency Patients.Diagnostics (Basel, Switzerland) · 2025Article
- Contrast medium dose optimization in the era of multi-energy CT.Japanese journal of radiology · 2025Review
- Risk of acute kidney injury following intravenous iodinated contrast exposure among pediatric population: a narrative review.Pediatric radiology · 2025Review
- AI-based automatic estimation of single-kidney glomerular filtration rate and split renal function using non-contrast CT.Insights into imaging · 2025Article
- The impact of chronic kidney disease on prognosis in acute stroke: unraveling the pathophysiology and clinical complexity for optimal management.Clinical and experimental nephrology · 2025Review
- Risk factors for and outcomes of acute kidney injury in ward-based hospital trauma admissions: A retrospective cohort analysis.PloS one · 2025Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIntravenous application of contrast media is part of a wide spectrum of diagnostic procedures for better imaging quality. Clinical avoidance of contrast-enhanced imaging is an ever-present quandary in patients with impaired kidney function. The objective of this study was to estimate the risk for acute kidney injury (AKI), dialysis and mortality among patients undergoing contrast-enhanced CT compared to propensity score-matched controls (i.e. contrast-unenhanced CT). Selected cohort studies featured high-risk patients with advanced kidney disease and critical illness.
methodsThis review was designed to conform to the Preferred Reporting Items in Systematic Reviews and Meta-Analysis (PRISMA) guidelines. PubMed was searched from August 2021 to November 2021 for all-language articles without date restriction. A random-effects model (DerSimonian and Laird method) was used for meta-analysis.
resultsTwenty-one articles were included, comprising data of 169,455 patients. The overall risk of AKI was similar in the contrast-enhanced and unenhanced groups (OR: 0.97 [95% CI: 0.85; 1.11], p = 0.64), regardless of baseline renal function and underlying disease. Substantial heterogeneity was detected (I
conclusionsBased on propensity score-matched pairs obtained from 21 cohort studies, we found no evidence for increased risk for AKI, dialysis or mortality after contrast-enhanced CT among patients with eGFR ≥ 45 mL/min/1.73 m KEY POINTS: • The application of contrast media for medical imaging is not associated with higher odds for AKI, induction of renal replacement therapy, or mortality. Many comorbidities traditionally associated with greater risk for acute kidney injury do not appear to predispose for renal decline after contrast media exposure. • Underlying hypertension and eGFR less than or equal to 30 mL/min/1.73 m
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.