ArticlemBio2022
Bacterial Signatures of Cerebral Thrombi in Large Vessel Occlusion Stroke.
Article in mBio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06935279 (Bacteria in Atherosclerotic Plaques and Adverse Events), which is not on this map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Bacteria in Atherosclerotic Plaques and Adverse Events
Who cites it
9 citing papers in PubMed, 18 citations in OpenAlex.
- A Review on the Role of Oral Bacteria in Stroke.International journal of molecular sciences · 2025Review
- Multi-omics profiling reveals key microbial and metabolic variations in ischemic stroke: insights into gut and oral microbiota.Archives of microbiology · 2025Article
- Metagenomic Insights into Microbial Signatures in Thrombi from Acute Ischemic Stroke Patients Undergoing Endovascular Treatment.Brain sciences · 2025Article
- Microbial Heterogeneity Identification of Cerebral Thrombi Via Metagenomic Next-Generation Sequencing-Based Strategy.Journal of the American Heart Association · 2024Article
- Review
- Bacterial signature in retrieved thrombi of patients with acute ischemic stroke-a systematic review.Therapeutic advances in neurological disorders · 2024Review
- Mendelian Randomization Highlights Gut Microbiota of Short-chain Fatty Acids' Producer as Protective Factor of Cerebrovascular Disease.Current neurovascular research · 2024Article
- Comprehensive analysis of the microbiome and metabolome in pus from pyogenic liver abscess patients with and without diabetes mellitus.Frontiers in microbiology · 2023Article
- Gut microbiome-based noninvasive diagnostic model to predict acute coronary syndromes.Frontiers in cellular and infection microbiology · 2023Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is important to understand the microbial features of the cerebral thrombus and its clinical relevance in stroke patients, of which data were scarce. We aimed to investigate the microbial features of cerebral thrombi retrieved via thrombectomy in stroke patients with large vessel occlusion (LVO) and their correlations with 3-month mortality. In a prospective cohort study, thrombus samples were collected during mechanical thrombectomy in LVO stroke patients with successful revascularization at a tertiary hospital. Oral, fecal, and isolated plasma samples were collected within 12 h of admission. The microbial compositions of all samples were compared using 16S rRNA gene amplicon next-generation sequencing. Fluorescent
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.