ArticleeLife2022
Sigma oscillations protect or reinstate motor memory depending on their temporal coordination with slow waves.
Article in eLife, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Pooled it
- Sex differences in electrical activity of the brain during sleep: a systematic review of electroencephalographic findings across the human lifespan.Biomedical engineering online · 2025Pooled it
- Efficacy and mechanisms of repeated closed-loop auditory exposure during slow-wave sleep for internet gaming disorder.Molecular psychiatry · 2025Trial
- A Single Night in Hypoxia Either with or without Ketone Ester Ingestion Reduces Sleep Quality without Impacting Next-Day Exercise Performance.Medicine and science in sports and exercise · 2025Trial
- Temporal sleep spindle clustering and slow-oscillation coupling in motor memory consolidation and generalization.Communications biology · 2026Article
- Personalized targeted memory reactivation enhances consolidation of challenging memories via slow wave and spindle dynamics.NPJ science of learning · 2025Article
- Article
- Novel murine closed-loop auditory stimulation paradigm elicits macrostructural sleep benefits in neurodegeneration.Journal of sleep research · 2025Article
- Unraveling the neurophysiological correlates of phase-specific enhancement of motor memory consolidation via slow-wave closed-loop targeted memory reactivation.Nature communications · 2025Article
- Article
- Sleep benefits perceptual but not movement-based learning of locomotor sequences.Scientific reports · 2024Article
- Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Targeted memory reactivation (TMR) during post-learning sleep is known to enhance motor memory consolidation but the underlying neurophysiological processes remain unclear. Here, we confirm the beneficial effect of auditory TMR on motor performance. At the neural level, TMR enhanced slow wave (SW) characteristics. Additionally, greater TMR-related phase-amplitude coupling between slow (0.5-2 Hz) and sigma (12-16 Hz) oscillations after the SW peak was related to higher TMR effect on performance. Importantly, sounds that were not associated to learning strengthened SW-sigma coupling at the SW trough. Moreover, the increase in sigma power nested in the trough of the potential evoked by the unassociated sounds was related to the TMR benefit. Altogether, our data suggest that, depending on their precise temporal coordination during post learning sleep, slow and sigma oscillations play a crucial role in either memory reinstatement or protection against irrelevant information; two processes that critically contribute to motor memory consolidation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.