Evidence map›Paper›PMID 35726602›Full record

ArticleThe Journal of international medical research2022

Mutation spectrum associated with metastasis of advanced cholangiocarcinoma.

Hao Song, Yao Huang, Xiaoqing Jiang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of international medical research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Observational
  3. Advances in the role of SWI/SNF complexes in tumours.Journal of cellular and molecular medicine · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Hao SongDepartment of Organ Transplantation, Eastern Hepatobiliary Surgery Hospital Affiliated to Shanghai Second Military Medical University, Shanghai, China.ORCID https://orcid.org/0000-0001-7180-3343
Yao HuangDepartment of Transplantation, Xinhua Hospital Affiliated to Shanghai JiaoTong University School of Medicine, Shanghai, China.
Xiaoqing JiangDepartment of Biliary Surgery, Eastern Hepatobiliary Surgery Hospital Affiliated to Shanghai Second Military Medical University, Shanghai, China.
Second Military Medical University · CNShanghai Jiao Tong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe mutations associated with metastasis in advanced-stage cholangiocarcinoma (CCA) have not been investigated.

objectiveTo explore mutations in patients with advanced CCA and independent factors related to metastasis.

methodsThis retrospective study performed next-generation sequencing of tumor specimens from patients with advanced CCA treated between January 2017 and December 2019. Tumor mutational burden (TMB), microsatellite instability, and programmed cell death ligand (PD-L)1 positivity were determined. Factors independently associated with metastasis were explored via logistic regression.

resultsNinety-one patients were included in this study.

conclusionsA history of biliary surgery and mutations in

Indexed as

Bile Duct NeoplasmsCholangiocarcinomaBile Ducts, IntrahepaticBiomarkers, TumorHumansMutationRetrospective StudiesBiomarkers, Tumoradvanced stageCholangiocarcinomahigh-throughput nucleotide sequencingmetastasismultivariable analysismutation

Identifiers

PMID35726602
PMCPMC9218467
OpenAlexW4283213842

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.