Evidence map›Paper›PMID 35726315›Full record

ArticleSTAR protocols2022

SPIKES: Identification of physicochemical properties of spike proteins across diverse host species of SARS-CoV-2.

Srinivasulu Yerukala Sathipati, Ming-Ju Tsai, Tonia Carter, Sanjay K Shukla, Shinn-Ying Ho

Abstract read
In one paragraph

Article in STAR protocols, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Srinivasulu Yerukala SathipatiCenter for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, WI, USA. Electronic address: sathipathi.srinivasulu@marshfieldclinic.org.
Ming-Ju TsaiHinda and Arthur Marcus Institute for Aging Research at Hebrew Senior Life, Boston, MA, USA; Department of Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Tonia CarterCenter for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Sanjay K ShuklaCenter for Precision Medicine Research, Marshfield Clinic Research Institute, Marshfield, WI, USA.
Shinn-Ying HoInstitute of Bioinformatics and Systems Biology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Department of Biological Science and Technology, National Yang Ming Chiao Tung University, Hsinchu, Taiwan; Center for intelligent Drug Systems and Smart Bio-Devices (IDS(2)B), National Yang Ming Chiao Tung University, Hsinchu, Taiwan; College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We describe a protocol to identify physicochemical properties using amino acid sequences of spike (S) proteins of SARS-CoV-2. We present an S protein prediction technique named SPIKES, incorporating an inheritable bi-objective combinatorial genetic algorithm to determine the host species specificity. This protocol addresses the S protein amino acid sequence data collection, preprocessing, methodology, and analysis. For complete details on the use and execution of this protocol, please refer to Yerukala Sathipati et al. (2022).

Indexed as

SARS-CoV-2Spike Glycoprotein, CoronavirusHost SpecificitySpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2BioinformaticsMicrobiologyProteomicsSystems biology

Identifiers

PMID35726315
PMCPMC9127179

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.