Evidence map›Paper›PMID 35725616›Full record

ArticleTrials2022

Bringing rehabilitation home with an e-health platform to treat stroke patients: study protocol of a randomized clinical trial (RGS@home).

Anna Mura, Martina Maier, Belén Rubio Ballester, Javier De la Torre Costa, Judit López-Luque, Axelle Gelineau, Stephane Mandigout, Per Hamid Ghatan, Raffaele Fiorillo, Fabrizio Antenucci and 11 more

2 registry-linked trialsOpen access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in Trials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04620707 naunknown statusnot on this map

RGS@Home Project: Scaling ICT Based Neurorehabilitation to Personalized 24/7 Home Care Post-stroke

TypeinterventionalSponsorInstitute for Bioengineering of CataloniaRan2020 to 2022Enrolled90ConditionsHemiparesis, Poststroke/CVA, Stroke, Acute, Motor DisordersArmsRGS based training and monitoring, Therapy as usual
NCT06558591 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Feasibility and Potential Impact of an Individualized Exercise Program Via a Telerehabilitation Device in Chronic Patients: A Pilot Study

TypeinterventionalSponsorLimoges UniversityRan2025 to 2027Enrolled50ConditionsChronic Disease, Chronic Condition, Stroke Sequelae, Age ProblemArmsTelerehabilitation intervention
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 9 institutions in 4 countries.

Anna MuraLaboratory of Synthetic, Perceptive, Emotive and Cognitive Systems (SPECS), Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain.
Martina MaierLaboratory of Synthetic, Perceptive, Emotive and Cognitive Systems (SPECS), Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain.
Belén Rubio BallesterLaboratory of Synthetic, Perceptive, Emotive and Cognitive Systems (SPECS), Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain.
Javier De la Torre CostaLaboratory of Synthetic, Perceptive, Emotive and Cognitive Systems (SPECS), Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain.
Judit López-LuqueInstitut de Recerca Sant Joan de Déu, Barcelona, Spain.
Axelle GelineauHAVAE Laboratory EA 6310, University of Limoges, Limoges, France.
Stephane MandigoutHAVAE Laboratory EA 6310, University of Limoges, Limoges, France.
Per Hamid GhatanUppsala University Hospital (UUH), Uppsala, Sweden.
Raffaele FiorilloInstitut de Recerca Sant Joan de Déu, Barcelona, Spain.
Fabrizio AntenucciSaddle Point Science Ltd., London, UK.
Ton CoolenFondation de l'Avenir pour la recherche médicale, Paris, France.
Iñigo ChiviteInstitut de Recerca Sant Joan de Déu, Barcelona, Spain.
Antonio CallenInstitut de Recerca Sant Joan de Déu, Barcelona, Spain.
Hugo LandaisEodyne Systems S.L., Barcelona, Spain.
Olga Irina GómezMedtronic Ibérica S.A., C/María de Portugal 11, Madrid, Spain.
Cristina MeleroMedtronic Ibérica S.A., C/María de Portugal 11, Madrid, Spain.
Santiago BrandiEodyne Systems S.L., Barcelona, Spain.
Marc DomenechEodyne Systems S.L., Barcelona, Spain.
Jean-Christophe DavietDepartment of Physical Medicine and Rehabilitation, University Hospital Center of Limoges, Limoges, France.
Riccardo ZuccaHospital del Mar Medical Research Institute Foundation, IMIM, Barcelona, Spain.
Paul F M J VerschureLaboratory of Synthetic, Perceptive, Emotive and Cognitive Systems (SPECS), Institute for Bioengineering of Catalonia (IBEC), Barcelona, Spain. paul.verschure@specs-lab.com.ORCID http://orcid.org/0000-0003-3643-9544
Institute for Bioengineering of Catalonia · ESParc Sanitari Sant Joan de Déu · ESUniversité de Limoges · FRMedtronic (Spain) · ESFondation de l'Avenir · FRHospital del Mar Research Institute · ESInstitució Catalana de Recerca i Estudis Avançats · ESSaddle Point Science (United Kingdom) · GBUppsala University Hospital · SE

Funding

EIT Health 19277
6 · The paper itself

Abstract

backgroundThere is a pressing need for scalable healthcare solutions and a shift in the rehabilitation paradigm from hospitals to homes to tackle the increase in stroke incidence while reducing the practical and economic burden for patients, hospitals, and society. Digital health technologies can contribute to addressing this challenge; however, little is known about their effectiveness in at-home settings. In response, we have designed the RGS@home study to investigate the effectiveness, acceptance, and cost of a deep tech solution called the Rehabilitation Gaming System (RGS). RGS is a cloud-based system for delivering AI-enhanced rehabilitation using virtual reality, motion capture, and wearables that can be used in the hospital and at home. The core principles of the brain theory-based RGS intervention are to deliver rehabilitation exercises in the form of embodied, goal-oriented, and task-specific action.

methodsThe RGS@home study is a randomized longitudinal clinical trial designed to assess whether the combination of the RGS intervention with standard care is superior to standard care alone for the functional recovery of stroke patients at the hospital and at home. The study is conducted in collaboration with hospitals in Spain, Sweden, and France and includes inpatients and outpatients at subacute and chronic stages post-stroke. The intervention duration is 3 months with assessment at baseline and after 3, 6, and 12 months. The impact of RGS is evaluated in terms of quality of life measurements, usability, and acceptance using standardized clinical scales, together with health economic analysis. So far, one-third of the patients expected to participate in the study have been recruited (N = 90, mean age 60, days after stroke ≥ 30 days). The trial will end in July 2023. DISCUSSION: We predict an improvement in the patients' recovery, high acceptance, and reduced costs due to a soft landing from the clinic to home rehabilitation. In addition, the data provided will allow us to assess whether the prescription of therapy at home can counteract deterioration and improve quality of life while also identifying new standards for online and remote assessment, diagnostics, and intervention across European hospitals.

trial registrationC linicalTrials.gov NCT04620707. Registered on November 3, 2020.

Indexed as

StrokeStroke RehabilitationTelemedicineHumansMiddle AgedQuality of LifeRandomized Controlled Trials as TopicRecovery of FunctionDeep techE-healthHome treatmentMotor recoveryRandomized clinical trialStrokeUpper extremitiesVirtual realityWearables

Identifiers

PMID35725616
PMCPMC9207837
OpenAlexW4283163667

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.