ArticleBMC oral health2022
Preventive potential of nano silver fluoride versus sodium fluoride varnish on enamel caries like lesions in primary teeth: in vitro study.
Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 8 citations in OpenAlex.
- Potential Applications of Nano Silver Fluoride in the Prevention of Dental Caries in Older Adults: A Scoping Review.Gerodontology · 2026Article
- Article
- Comparison of Remineralization Potential of Different Remineralizing Agents on Carious Lesion of Primary Teeth: A Systematic Review and Meta-analysis.International journal of clinical pediatric dentistry · 2026Article
- Effect of nanosilver fluoride versus silver diamine fluoride on shear bond strength and color change of resin-modified glass ionomer cement bonded to artificial dentin caries: an in-vitro study.BMC oral health · 2026Article
- Assessment of the remineralizing potential of nano-bioactive glass, nano-hydroxyapatite, and sodium fluoride on artificial carious lesions in primary teeth.BMC oral health · 2026Article
- Evaluation of SMART technique using Nano-silver fluoride and Silver Diamine Fluoride; evaluation of tooth discoloration and shear bond strength in primary molars.The Saudi dental journal · 2026Article
- Evaluating the remineralisation potential and clinical evidence of emerging biocompatible materials in restorative dentistry: a systematic review.Biomaterial investigations in dentistry · 2026Review
- Antibacterial activity and physicochemical properties of light-curable fluoride varnishes containing strontium phosphate-based glass.Clinical oral investigations · 2025Article
- Synergistic effect of nanosilver fluoride with L-arginine on remineralization of early carious lesions.Scientific reports · 2025Article
- Remineralizing effect of NSF on artificial enamel caries.BMC oral health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundProfessionally applied topical fluoride preparations have been commonly used and have proven to prevent dental decay. Alternative preparations that provide further benefits may be of interest to investigate. This study aimed to investigate the effect of experimental nano silver fluoride (NSF) formulation compared to commercial sodium fluoride varnish (FV) on prevention of in vitro demineralization of initially sound enamel in primary teeth.
methodsForty-eight extracted/exfoliated sound molars were sectioned buccolingually into 96 specimens then assigned randomly into two equal groups. Each group was further subdivided into two equal subgroups (Ia: NSF, IIa: FV, Ib and IIb as negative controls). The test materials were applied, then all the specimens were subjected to a demineralization pH cycling model for 7 days. Specimens were examined for surface microhardness using Vickers microhardness device and lesion depth was evaluated by polarized light microscope using image J 1.46r software. Data were analyzed using paired t-test, independent t-test, and Mann Whitney U test.
resultsThe test materials were significantly superior to their negative controls, (P < 0.001) and comparable to each other, (P > 0.05) regarding microhardness and lesion depth. In comparison to FV, NSF showed lower yet statistically insignificant percent increase in microhardness and decrease in lesion depth, (P = 0.81, 0.86, respectively). Qualitative evaluation revealed that both agents reduced the lesion depth formation.
conclusionNSF showed similar effect to that of FV in limiting in vitro enamel demineralization caused by acidic challenge. Hence, it could be regarded as a promising alternative preventive agent in primary teeth.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.