ArticleBMC ophthalmology2022
Optical coherence tomographic angiography in children with anisometropic amblyopia.
Article in BMC ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 8 citations in OpenAlex.
- Macular and optic disc vascular densities measured by optical coherence tomography angiography in pediatric patients with different amblyopia types.BMC ophthalmology · 2025Article
- Choroidal vascular characteristics in anisometropic amblyopia: a comparative analysis.BMC ophthalmology · 2025Article
- Article
- OCT-Angiography Findings in Children with Anisometropic Amblyopia.Children (Basel, Switzerland) · 2023Article
- The Relationship between Fixation Stability and Retinal Structural Parameters in Children with Anisometropic, Strabismic and Mixed Amblyopia.Life (Basel, Switzerland) · 2023Article
- Evaluation of Foveal Avascular Zone After Strabismic and Anisometropic Amblyopia Therapy in Saudi Children Using Optic Coherence Tomography Angiography: A Cohort Study.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo observe and compare the difference in retinal perfusion using optical coherence tomography angiography (OCTA) between anisometropic amblyopia in children and fellow eyes as well as age-matched controls.
methodsA total of 16 children with anisometropic amblyopia and 19 age-matched healthy subjects were enrolled. All participants underwent OCTA examination, with 3 mm × 3 mm and 6 mm × 6 mm scans in the macular region. Perfusion parameters of the superficial retinal layer were measured by built-in software, including the macular foveal avascular zone (FAZ) area, perimeter and circularity, as well as the vessel length density (VLD) and perfusion density (PD) of the foveal, parafoveal and perifoveal regions.
resultsAmong the 16 patients with anisometropic amblyopia, the FAZ area was significantly higher in diseased eyes (P = 0.027) than in fellow eyes. The VLD and PD of the foveal average and the VLD of the nasal quadrant of the perifoveal region in anisometropic amblyopic eyes were significantly lower than those in fellow eyes (P < 0.05). The VLD of the parafoveal average, the superior, temporal, inferior and nasal quadrants of the parafoveal region, and the nasal quadrant of the perifoveal region in anisometropic amblyopic eyes were significantly lower than those in healthy controls (P < 0.05). The PD of the parafoveal average, and the inferior quadrant of the parafoveal region in anisometropic amblyopic eyes were significantly lower than those in healthy controls (P < 0.05). The VLD of the parafoveal average, the superior, inferior and nasal quadrants of the parafoveal region, and the nasal quadrant of the perifoveal region in fellow eyes were significantly lower than those in healthy controls (P < 0.05). The PD of the parafoveal average, and the inferior quadrant of the parafoveal region in fellow eyes were significantly lower than those in healthy controls (P < 0.05).
conclusionsThe macular vessel density of the superficial capillary plexus is lower in anisometropic amblyopic children than in age-matched healthy children. Compared with the fellow eye, the perfusion of the amblyopic eye in children with anisometropic amblyopia also decreases.
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