Evidence map›Paper›PMID 35725386›Full record

ArticleBMC genomics2022

HLA-E restricted cytomegalovirus UL40 peptide polymorphism may represent a risk factor following congenital infection.

David Tarragó, Irene González, Maria Francisca González-Escribano

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Investigation ofInternational journal of molecular sciences · 2025
    Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

David TarragóNational Center for Microbiology, Instituto de Salud Carlos III, Majadahonda- Pozuelo km 2, 28220 Majadahonda, Madrid, Spain. davtarrago@isciii.es.
Irene GonzálezNational Center for Microbiology, Instituto de Salud Carlos III, Majadahonda- Pozuelo km 2, 28220 Majadahonda, Madrid, Spain.
Maria Francisca González-EscribanoDepartment of Immunology, Virgen del Rocío Universitary Hospital (IBiS, CSIC, US), 41013, Seville, Spain.
Centro Nacional de Microbiologia · ESInstituto de Biomedicina de Sevilla · ES

Funding

Instituto de Salud Carlos III MPY1372/12
6 · The paper itself

Abstract

backgroundCongenital cytomegalovirus immunopathogenesis is largely unknown and multifactorial due to the complex interactions between viral, maternal, placental, and child factors. Polymorphisms in the HLA-E binding UL40

resultsNineteen different HLA-E binding UL40

conclusionsOur findings suggest that a mismatch between UL40

Indexed as

CytomegalovirusCytomegalovirus InfectionsHistocompatibility Antigens Class IViral ProteinsCD8-Positive T-LymphocytesChildFemaleHLA-A AntigensHLA-E AntigensHumansPeptidesPlacentaPregnancyRetrospective StudiesRisk FactorsHistocompatibility Antigens Class IHLA-A AntigensHLA-E AntigensPeptidesUL40 glycoprotein, CytomegalovirusViral ProteinsCongenital CMVHLA-EImmunomodulatory geneUL40 peptideUL40 variability

Identifiers

PMID35725386
PMCPMC9208114
OpenAlexW4283158402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.