Evidence map›Paper›PMID 35725136›Full record

ArticleAmerican journal of preventive medicine2022

Race Versus Social Determinants of Health in COVID-19 Hospitalization Prediction.

Carrie R Howell, Li Zhang, Nengjun Yi, Tapan Mehta, W Timothy Garvey, Andrea L Cherrington

Abstract read
In one paragraph

Article in American journal of preventive medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. How well can commonly used anxiety scales detect treatment outcomes in the context of autism?Autism : the international journal of research and practice · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Carrie R HowellDivision of Preventive Medicine, Department of Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama. Electronic address: chowell@uabmc.edu.
Li ZhangDepartment of Biostatistics, School of Public Health, The University of Alabama at Birmingham, Birmingham, Alabama.
Nengjun YiDepartment of Biostatistics, School of Public Health, The University of Alabama at Birmingham, Birmingham, Alabama.
Tapan MehtaDepartment of Health Services Administration, School of Health Professions, The University of Alabama at Birmingham, Birmingham, Alabama.
W Timothy GarveyDepartment of Nutrition Sciences, School of Health Professions, The University of Alabama at Birmingham, Birmingham, Alabama.
Andrea L CherringtonDivision of Preventive Medicine, Department of Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama.

Funding

Project 2: Leveraging Ongoing Home Visitation Programs to Address Obesity Disparities among Underserved, Low-Income Mothers and ChildrenU54MD000502 · NIMHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N., GARVEY, W TIMOTHY · 2017 to 2022
$11.8M
NIMHD NIH HHS U54 MD000502
6 · The paper itself

Abstract

introductionIncluding race as a biological construct in risk prediction models may guide clinical decisions in ways that cause harm and widen racial disparities. This study reports on using race versus social determinants of health (SDoH) in predicting the associations between cardiometabolic disease severity (assessed using cardiometabolic disease staging) and COVID-19 hospitalization.

methodsElectronic medical record data on patients with a positive COVID-19 polymerase chain reaction test in 2020 and a previous encounter in the electronic medical record where cardiometabolic disease staging clinical data (BMI, blood glucose, blood pressure, high-density lipoprotein cholesterol, and triglycerides) were available from 2017 to 2020, were analyzed in 2021. Associations between cardiometabolic disease staging and COVID-19 hospitalization adding race and SDoH (individual and neighborhood level [e.g., Social Vulnerability Index]) in different models were examined. Area under the curve was used to assess predictive performance.

resultsA total of 2,745 patients were included (mean age of 58 years, 59% female, 47% Black). In the cardiometabolic disease staging model, area under the curve was 0.767 vs 0.777 when race was included. Adding SDoH to the cardiometabolic model improved the area under the curve to 0.809 (p<0.001), whereas the addition of SDoH and race increased the area under the curve to 0.811. In race-stratified models, the area under the curve for non-Hispanic Blacks was 0.781, whereas the model for non-Hispanic Whites performed better with an area under the curve of 0.821.

conclusionsCardiometabolic disease staging was predictive of hospitalization after a positive COVID-19 test. Adding race did not markedly increase the predictive ability; however, adding SDoH to the model improved the area under the curve to ≥0.80. Future research should include SDoH with biological variables in prediction modeling to capture social experience of race.

Indexed as

Cardiovascular DiseasesCOVID-19FemaleHospitalizationHumansMaleMiddle AgedSocial Determinants of HealthWhite People

Identifiers

PMID35725136
PMCPMC9212800

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.