Evidence map›Paper›PMID 35724965›Full record

ArticleThe clinical respiratory journal2022

Metagenomic next-generation sequencing for the diagnosis of Chlamydia psittaci pneumonia.

Hu Li, Binwei Hao, Yongxue Wang, Dinghong Yu, Zhonghua Chen, Duanlin Du, Jian Xiong, Kang Li, Hengping Zhang, Xu Liu and 4 more

Abstract read
In one paragraph

Article in The clinical respiratory journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Rapid diagnosis ofExperimental and therapeutic medicine · 2026
    Article
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  3. Successful azithromycin treatment ofFrontiers in pharmacology · 2026
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  4. SevereFrontiers in medicine · 2026
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  5. The relationship betweenFrontiers in medicine · 2026
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  7. Frontiers in medicine · 2026
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  8. Liver Function Abnormalities in Patients withInfection and drug resistance · 2025
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  9. Virulence · 2024
    Review
  10. Article
  11. Analysis and Perception ofInfection and drug resistance · 2024
    Article
  12. Frontiers in medicine · 2024
    Article
  13. Observational
  14. Article
  15. Article
  16. Clinical features and risk factors of liver injury in patients withFrontiers in cellular and infection microbiology · 2023
    Article
  17. Infection and drug resistance · 2023
    Article
  18. Article
  19. Article
  20. Case report: A clinical case study of six patients withFrontiers in cellular and infection microbiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Hu LiDepartment of Imaging, Yueyang Central Hospital, Yueyang, Hunan, China.
Binwei HaoDepartment of Pulmonary and Critical Care Medicine, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, China.
Yongxue WangDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Dinghong YuDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Zhonghua ChenDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Duanlin DuDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Jian XiongDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Kang LiDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Hengping ZhangDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Xu LiuDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Kai LiuDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Fanrong XiaoDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Xiaosan ChengDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.
Lingmei HuangDepartment of Pulmonary and Critical Care Medicine, Yueyang Central Hospital, Yueyang, Hunan, China.

Funding

Basic Research Guiding Program Project of Yueyang City 2020-21National Natural Science Foundation of China 82100053
6 · The paper itself

Abstract

The aim of this study was to investigate the clinical characteristics of Chlamydia psittaci pneumonia and evaluate the diagnostic value of Metagenomic Next-Generation Sequencing (mNGS). A total of 44 patients diagnosed with Chlamydia psittaci pneumonia using mNGS were retrospectively analysed. The demographic and clinical features, laboratory data, imaging findings and clinical outcomes were collected. Results showed that 65.91% of the patients had a history of exposure to poultry or birds. All patients presented with fever. Apart from systemic and respiratory symptoms, some patients also presented with digestive and neurological symptoms. Respiratory failure was common among patients. The key laboratory tests were normal white blood cell counts, slightly elevated PCT, changes in levels of cardiac enzymes, liver enzymes and hyponatremia. Chest imaging revealed that most of the lesions contained patchy exudation or lobar consolidation of one lobe, especially in the lower lobe. Consolidation of both lungs was seen in critically ill patients. Although quinolones were effective in most patients, tetracyclines should be the first choice of treatment. The overall prognosis was good; however, patients who developed severe pneumonia had poor prognosis. The incidence of chlamydia psittaci pneumonia may be underestimated due to the nonspecific clinical manifestations and lack of confirmatory testing methods. The use of mNGS has increased the number of patients diagnosed with chlamydia psittaci pneumonia. mNGS is an effective diagnostic method for chlamydia psittaci pneumonia.

Indexed as

Chlamydophila psittaciPneumoniaPsittacosisAnimalsBirdsHigh-Throughput Nucleotide SequencingHumansPoultryRetrospective StudiesChlamydia psittaciclinical analysismetagenomic next-generation sequencingpneumonia

Identifiers

PMID35724965
PMCPMC9329019

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.