Evidence map›Paper›PMID 35724686›Full record

ArticleInternational journal of epidemiology2023

Worth the paper it's written on? A cross-sectional study of Medical Certificate of Stillbirth accuracy in the UK.

Michael P Rimmer, Ian Henderson, William Parry-Smith, Olivia Raglan, Jennifer Tamblyn, Alexander E P Heazell, Lucy E Higgins, UKARCOG NESTT working group authors

Abstract read
In one paragraph

Article in International journal of epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Glycaemic control in labour with diabetes: GILD, a scoping study.Health technology assessment (Winchester, England) · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael P RimmerUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.
Ian HendersonUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.
William Parry-SmithUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.
Olivia RaglanUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.
Jennifer TamblynUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.
Alexander E P HeazellMaternal and Fetal Health Research Centre, University of Manchester, Manchester, UK.
Lucy E HigginsUnited Kingdom Audit and Research Collaborative in Obstetrics and Gynaecology, UK.ORCID 0000-0003-0993-497X
UKARCOG NESTT working group authors

Funding

Department of HealthMedical Research Council MR/N022556/1
6 · The paper itself

Abstract

backgroundThe Medical Certificate of Stillbirth (MCS) records data about a baby's death after 24 weeks of gestation but before birth. Major errors that could alter interpretation of the MCS were widespread in two UK-based regional studies.

methodsA multicentre evaluation was conducted, examining MCS issued 1 January 2018 to 31 December 2018 in 76 UK obstetric units. A systematic case-note review of stillbirths was conducted by Obstetric and Gynaecology trainees, generating individual 'ideal MCSs' and comparing these to the actual MCS issued. Anonymized central data analysis described rates and types of error, agreement and factors associated with major errors.

resultsThere were 1120 MCSs suitable for assessment, with 126 additional submitted data sets unsuitable for accuracy analysis (total 1246 cases). Gestational age demonstrated 'substantial' agreement [K = 0.73 (95% CI 0.70-0.76)]. Primary cause of death (COD) showed 'fair' agreement [K = 0.26 (95% CI 0.24-0.29)]. Major errors [696/1120; 62.1% (95% CI 59.3-64.9%)] included certificates issued for fetal demise at <24 weeks' gestation [23/696; 3.3% (95% CI 2.2-4.9%)] or neonatal death [2/696; 0.3% (95% CI 0.1-1.1%)] or incorrect primary COD [667/696; 95.8% (95% CI 94.1-97.1%)]. Of 540/1246 [43.3% (95% CI 40.6-46.1%)] 'unexplained' stillbirths, only 119/540 [22.0% (95% CI 18.8-25.7%)] remained unexplained; the majority were redesignated as either fetal growth restriction [FGR: 195/540; 36.1% (95% CI 32.2-40.3%)] or placental insufficiency [184/540; 34.1% (95% CI 30.2-38.2)]. Overall, FGR [306/1246; 24.6% (95% CI 22.3-27.0%)] was the leading primary COD after review, yet only 53/306 [17.3% (95% CI 13.5-22.1%)] FGR cases were originally attributed correctly.

conclusionThis study demonstrates widespread major errors in MCS completion across the UK. MCS should only be completed following structured case-note review, with particular attention on the fetal growth trajectory.

Indexed as

PlacentaStillbirthCross-Sectional StudiesFemaleFetal DeathGestational AgeHumansInfant, NewbornPregnancyUnited Kingdomaccuracycause of deathdeath certificationfetal growth restrictionperinatal deathplacental insufficiencyStillbirthstillbirth certification

Identifiers

PMID35724686
PMCPMC9908049

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