Evidence map›Paper›PMID 35724613›Full record

ArticleClinical neurology and neurosurgery2022

Treatment of tegmen dehiscence using a middle fossa approach and autologous temporalis fascia graft: Outcomes from a single center.

James Swanson, William Oetojo, Zachary Uram, Ignacio Jusue-Torres, Jehad Zakaria, Matthew L Kircher, Anand V Germanwala

Open access · greenAbstract read
In one paragraph

Article in Clinical neurology and neurosurgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Risk Reduction of Recurrent Cerebrospinal Fluid Leaks With Postoperative Intracranial Pressure Management: A Systematic Review.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
    Pooled it
  2. Surgical Outcomes Comparison of Spontaneous Middle Cranial Fossa Cerebrospinal Fluid Leaks: Systematic Review and Meta-analysis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Pooled it
  3. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

James SwansonStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
William OetojoStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Zachary UramStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA.
Ignacio Jusue-TorresDepartment of Neurological Surgery, Loyola University Medical Center, Maywood, IL, USA.
Jehad ZakariaDepartment of Neurological Surgery, Loyola University Medical Center, Maywood, IL, USA.
Matthew L KircherStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA; Department of Otolaryngology, Loyola University Medical Center, Maywood, IL, USA.
Anand V GermanwalaStritch School of Medicine, Loyola University Chicago, Maywood, IL, USA; Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL, USA; Department of Otolaryngology, Loyola University Medical Center, Maywood, IL, USA. Electronic address: anand.germanwala@lumc.edu.
Loyola University Chicago · USLoyola University Medical Center · USNeurological Surgery · US

Funding

Summer Research Experience for Medical Students in Inflammation and Infectious DiseasesT35AI125220 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI Edward M. Campbell, Simon Kaja · 2017 to 2026
$510k
NIAID NIH HHS T35 AI125220
6 · The paper itself

Abstract

introductionAlthough bony defects of the tegmen surface are relatively common, the majority of dehiscences are asymptomatic. For those who experience symptoms, there is a wide spectrum of relatively benign manifestations such as hearing loss and otorrhea to potentially more serious but rare sequelae such as epilepsy and meningitis. Surgical management of tegmen dehiscences (TDs) can help prevent these symptoms. In this manuscript, we present one of the largest reported single team experiences of using a temporal craniotomy with middle cranial fossa approach and temporalis fascia graft in the treatment of tegmen defects.

methodsWe retrospectively reviewed every case of a TD surgically repaired by the same neurosurgeon/otolaryngologist team at Loyola University Medical Center from May 2015 to January 2022. In our chart review, we identified 44 patients with 48 cases of tegmen defect repair. We analyzed patient characteristics, operative details, and postoperative outcomes.

results44 patients met inclusion criteria for the presence of TD (mean age 55 years, 55% male, and average body mass index 35.6). 89% of these patients had no clear etiology for the dehiscence. Commonly reported symptoms were hearing loss (89%) and CSF otorrhea (82%). The least reported presenting signs and symptoms were seizures (5%) and meningitis (2%). Most defects were repaired with both temporalis fascial and calvarial bone grafts (63%), while a minority were treated with temporalis fascia only (33%), temporalis fascia with muscle (2%), or fascia lata (2%). Every patient in our sample experienced resolution of CSF otorrhea after tegmen repair and 81% of the sample reported subjective hearing improvements after surgery. 6% of our sample had post-operative infections and 8% of patients underwent repeat unilateral surgery for a surgical complication.

conclusionCraniotomy for middle fossa approach using autologous temporalis fascial grafts is a safe and effective method for the treatment of TD. These procedures should be performed by experienced and multidisciplinary teams.

Indexed as

Cerebrospinal Fluid OtorrheaHearing LossCranial Fossa, MiddleFasciaFemaleHumansMaleMiddle AgedRetrospective StudiesTemporal BoneMiddle Fossa ApproachTegmen Dehiscence

Identifiers

PMID35724613
PMCPMC10171465
OpenAlexW4281952701

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.