Evidence map›Paper›PMID 35723821›Full record

ReviewWiener medizinische Wochenschrift (1946)2024

Association between sex and Huntington's disease: an updated review on symptomatology and prognosis of neurodegenerative disorders.

Nimra Hasnain, Taha Bin Arif, Roha Shafaut, Faiza Zakaria, Syeda Zainab Fatima, Ibtehaj Ul Haque

Abstract readReview
PubMed Publisher
In one paragraph

Review in Wiener medizinische Wochenschrift (1946), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Nimra HasnainDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Taha Bin ArifDow Medical College, Dow University of Health Sciences, Karachi, Pakistan. tahaarif20@yahoo.com.ORCID http://orcid.org/0000-0003-4879-560X
Roha ShafautDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Faiza ZakariaDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Syeda Zainab FatimaDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Ibtehaj Ul HaqueDow Medical College, Dow University of Health Sciences, Karachi, Pakistan.
Civil Hospital Karachi · PKDow University of Health Sciences · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huntington's disease is a rare autosomal dominant disorder presenting with chorea, rigidity, hypo-/akinesia, cognitive decline, and psychiatric disturbances. Numerous risk factors have been defined in the onset of this disease. However, the number of CAG repeats in the genes are the most crucial factor rendering patients susceptible to the disease. Studies have shown significant differences in onset and disease presentation among the sexes, which prompts analysis of the impact of different sexes on disease etiology and progression. This article therefore discusses the evidence-based role of sex in aspects of symptomatology, pathogenesis, biomarkers, progression, and prognosis of Huntington's disease, with a secondary review of sex-linked differences in Alzheimer's and Parkinson's disease.

Indexed as

Huntington DiseaseHumansPrognosisAutosomal dominantBiomarkerPathogenesisRisk factorsSex hormone

Identifiers

PMID35723821
OpenAlexW4283163680

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.