Evidence map›Paper›PMID 35723816›Full record

ArticleJournal of neuro-oncology2022

Utility of hospital frailty risk score for predicting postoperative outcomes in craniopharyngioma.

Racheal Peterson, Sandeep Kandregula, Elizabeth Jee, Bharat Guthikonda

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In one paragraph

Article in Journal of neuro-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Racheal PetersonDepartment of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.
Sandeep KandregulaDepartment of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.
Elizabeth JeeDepartment of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA.
Bharat GuthikondaDepartment of Neurosurgery, Louisiana State University Health Shreveport, 1501 Kings Highway, Shreveport, LA, 71103, USA. Bharat.Guthikonda@lsuhs.edu.
Louisiana State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

overviewFrailty is an age-associated decline in functional status leading to increased vulnerability to otherwise innocuous stressors. In neurosurgical patients, frailty has been associated with postoperative complications, increased mortality, longer hospitalization, and increased care costs for a variety of conditions. This study seeks to determine the association between frailty and postoperative outcomes in patients undergoing surgery for craniopharyngioma.

methodsThe Nationwide Inpatient Sample (NIS) database was queried for patients diagnosed with craniopharyngioma who underwent surgery via either craniotomy or transsphenoidal approach. Comorbid diagnoses were used to calculate the Hospital Frailty Risk Score (HFRS) and assign patients to low (< 5), intermediate (5-15), or high-risk (> 15) categories. Logistic regression was completed to determine whether the HFRS category was predictive of mortality, postoperative complication, extended hospitalization, or increased hospital costs compared to age.

resultsIncreased frailty score was predictive of increased length of stay, increased hospital costs, and non-home discharge in binary logistic regression with good discrimination on the ROC curve compared to age at admission. HFRS risk categories were significantly predictive of the development of any complication, with 100% of high-risk patients developing a complication compared to 76% of intermediate-risk and 63% of low-risk patients. HFRS risk categories were also predictive of the extended length of stay (71%, 49%, and 11% for high-, intermediate-, and low-risk, respectively) and non-home discharge (86%, 56%, and 17%). Regression analysis was unable to be performed for mortality due to the low number of deaths in the study group.

conclusionIn patients undergoing any surgery for craniopharyngioma, frailty is predictive of increased hospital length of stay and overall care costs. HFRS failed to independently predict mortality because the incidence of mortality is too low in this population to analyze. The HFRS is a valuable tool to identify post-operative outcomes following surgery for craniopharyngioma.

Indexed as

CraniopharyngiomaFrailtyPituitary NeoplasmsHospitalsHumansLength of StayPostoperative ComplicationsRetrospective StudiesRisk FactorsCraniopharyngiomaFrailtyPituitary surgerySkull base surgeryTranssphenoidal surgery

Identifiers

PMID35723816
OpenAlexW4283156417

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.