ArticleEJNMMI physics2022
Simplified dosimetry for kidneys and tumors in
Article in EJNMMI physics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 35 citations in OpenAlex.
- Fraction-dependent dose dynamics and clinical safety in high-risk neuroblastoma treated with [European journal of nuclear medicine and molecular imaging · 2026Trial
- Impact of simulation settings, time-activity curve integration range, and imaging time points on full Monte Carlo-basedAnnals of nuclear medicine · 2026Article
- Personalised Dosimetry in Nuclear Medicine: Bridging Physics, Biology and AI for Next Generation Radiopharmaceutical Therapy.Nuclear medicine and molecular imaging · 2026Review
- Inter-institutional variability in kidney dosimetry duringRadiological physics and technology · 2026Article
- Towards practical radiopharmaceutical treatment planning: a review of dosimetry simplification techniques.Theranostics · 2026Review
- Evaluation of using small volume of interest regions for clinical kidney dosimetry inEJNMMI physics · 2025Article
- A Monte Carlo study comparing dead-time losses of a gamma camera between tungsten functional paper and lead sheet for dosimetry in targeted radionuclide therapy with Lu-177.Annals of nuclear medicine · 2025Article
- Evolution of dosimetric parameters through PRRT and potential impact on clinical practice: data from the prospective phase II LUMEN study.EJNMMI research · 2024Article
- Estimation of kidney doses from [EJNMMI physics · 2024Article
- Organ and tumor dosimetry including method simplification for [EJNMMI physics · 2024Article
- Uncertainty Analysis of Time-Integrated Activity Coefficient in Single-Time-Point Dosimetry Using Bayesian Fitting Method.Nuclear medicine and molecular imaging · 2024Article
- Prediction of [EJNMMI physics · 2024Article
- A single-institution experience withFrontiers in oncology · 2024Article
- Comparative in vivo biodistribution of cells labelled with [EJNMMI research · 2023Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo evaluate if satisfactory post-therapeutic image-based dosimetry can be achieved for Lu-177-DOTATATE treatments using a reduced number of image acquisitions to improve patient comfort and reduce economical costs.
methods39 patients who underwent 147 treatment cycles of Lu-177-DOTATATE for neuroendocrine tumors were included in the study. A total of 291 and 284 absorbed doses were calculated to kidneys and tumors, respectively. Single-point dosimetry was performed using one SPECT/CT image acquired at 1 d or 7 d post-treatment using a fixed effective half-life (T
resultsAbsorbed doses to kidneys were most accurate when single-point dosimetry was performed using 1 d images with median ratios in relation to "true" doses in total dose of 1.00 (IQR: 0.97-1.03) when using fixed T
conclusionDosimetry can be performed with satisfactory accuracy when using single SPECT/CT images acquired at 1 d for kidneys or at 7 d for tumors.
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